Photo by Ryan Coleman

Sikeston Hotels

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Top 10 trending Sikeston hotels

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Will stay again"
The price is P5,761
P6,624 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1006)
"The staff was very friendly and the hotel was very clean!"
The price is P5,083
P5,734 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel Cape Girardeau Conference Center

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (722)
"Great place to stay convenient walking to multiple restaurants"
The price is P6,194
P6,987 total
includes taxes & fees
Jul 19 - Jul 20
Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Great place to stay with kids "
The price is P5,337
P6,136 total
includes taxes & fees
Jul 19 - Jul 20
Pear Tree Inn Sikeston

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay. "
The price is P5,152
P5,812 total
includes taxes & fees
Aug 1 - Aug 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (956)
"Room was very clean and staff was excellent!"
The price is P5,083
P5,734 total
includes taxes & fees
Jul 19 - Jul 20
Drury Inn & Suites Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Front desk staff was very friendly and helpful."
The price is P4,066
P4,587 total
includes taxes & fees
Jul 17 - Jul 18
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1009)
"Excellent place to stay "
The price is P3,812
P4,301 total
includes taxes & fees
Jul 17 - Jul 18
Pear Tree Inn Cape Girardeau Near the Medical Center

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (114)
"Hotel was very clean and the lady that checked us in was very friendly. "
The price is P5,253
P5,926 total
includes taxes & fees
Jul 20 - Jul 21
Fairfield Inn & Suites by Marriott Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (479)
"Good place "
The price is P5,377
P6,156 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Perryville by IHG

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (361)
"Clean, great breakfast, quiet, friendly staff"
The price is P6,674
P7,556 total
includes taxes & fees
Jul 19 - Jul 20
Hampton Inn Sikeston

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (334)
"Wonderful place to stay. Very clean and affordable!"
The price is P5,948
P6,710 total
includes taxes & fees
Jul 14 - Jul 15
The Riverview

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (452)
"Excellent stay!"
The price is P5,875
P6,520 total
includes taxes & fees
Aug 3 - Aug 4
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Great staff "
The price is P5,083
P5,374 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Jackson MO

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
10.0 out of 10, Exceptional, (13)
"Nice hotel "
The price is P6,891
P7,803 total
includes taxes & fees
Jul 20 - Jul 21
Fairfield Inn & Suites by Marriott Sikeston

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (877)
"Clean and convenient location "
The price is P3,841
P4,397 total
includes taxes & fees
Jul 20 - Jul 21
Super 8 by Wyndham Perryville

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (581)
"I liked that it was quiet and breakfast was good."
The price is P5,570
P6,028 total
includes taxes & fees
Jul 20 - Jul 21
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1011)
"We enjoyed our stay and the breakfast was good!"
The price is P4,977
P5,673 total
includes taxes & fees
Aug 10 - Aug 11
Best Western Plus Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (412)
"Overall a nice hotel, everything was clean and maintained, staff was helpful. We didn't realize there were no towels in the pool room til we were all wet, but made do with a couple from the gym next door😅 Breakfast was a great selection of hot and cold food options"
The price is P6,100
P6,907 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Sikeston Southwest by IHG

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (425)
"Unique place in a historic local building - the bank vault was cool!"
The price is P6,552
P7,425 total
includes taxes & fees
Jul 27 - Jul 28
Courtyard by Marriott Cape Girardeau Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston and related destinations

Explore Sikeston: its food, riverfront, museums, and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest by IHG. See all available top hotels, or vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Sikeston and Pear Tree Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best pet-friendly accommodation in Sikeston?

Best Western Plus Sikeston is a top hotel for people traveling with their pets, and offers an indoor pool and a fitness center for its human guests. Other good options for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What's the best hotel for a golf vacation in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.