Photo by Ryan Coleman

Luxury Hotels in Sikeston, Missouri

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Check availability on Sikeston Luxury Hotels

Tonight
Jun 29 - Jun 30
Tomorrow
Jun 30 - Jul 1
Next weekend
Jul 4 - Jul 6
In two weeks
Jul 11 - Jul 13

Top Sikeston Luxury Hotels

Days Inn and Suites by Wyndham Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1003)
"We were there to get a good nights sleep and we did."
The price is P4,567
P5,205 total
includes taxes & fees
Jul 9 - Jul 10
Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Great area. Great value"
The price is P3,308
P3,732 total
includes taxes & fees
Jul 3 - Jul 4
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (598)
"Great room, great experience "
The price is P3,620
P4,083 total
includes taxes & fees
Jun 30 - Jul 1
Quality Inn
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1007)
"Always the best hotel in any town. "
The price is P5,090
P5,851 total
includes taxes & fees
Jul 13 - Jul 14
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (948)
"Room was very clean and staff was excellent!"
The price is P5,938
P6,699 total
includes taxes & fees
Jun 30 - Jul 1
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you looking for a luxury hotel for your stay in Sikeston?
Use Expedia and let us help you arrange a flight to Cairo, IL (CIR-Cairo Regional) airport or Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Sikeston has to offer. During your visit, you might want to enjoy the shopping which Sikeston is known for.
How many luxury hotels will I find in Sikeston?
Lie in the lap of luxury during your getaway to Sikeston in one of Expedia's 5 luxury hotels.
When can I expect good weather in Sikeston?
Planning for the weather is a good way to make your trip to Sikeston relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do in Sikeston?
Experience all that Sikeston has to offer when you visit Sikeston Depot Museum, Central Park, and Front Street Studio & Art Gallery. If you have a little extra time during your trip, you might want to make a stop at Stoddard County Civil War Memorial Cemetery and Hunter-Dawson State Historic Site.