St. Charles Hotels

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jul 3 - Jul 4
Tomorrow
Jul 4 - Jul 5
This weekend
Jul 4 - Jul 6
Next weekend
Jul 11 - Jul 13

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending St. Charles hotels

White Valley Motel
Desk, rollaway beds, free WiFi, bed sheets

White Valley Motel

2.5 star property
5.8 out of 10, (110)
"Nice location, looks good on the outside, easy parking, bed good, shower good, comfortable interior temperature and pleasant atmosphere (air), service very good. Negatives- toilet seat loose, bathroom door drags on floor, tv had lines through screen and refrigerator worked but bably yellowed. Overall would stay again because of good price, location and service."
The price is P3,887
P4,335 total
includes taxes & fees
Jul 4 - Jul 5
White Valley Motel
The Wen Inn formerly Andor Wenneson
Exterior

The Wen Inn formerly Andor Wenneson

2.0 star property
10.0 out of 10, Exceptional, (31)
"The hotel was beautiful, clean! Added bnus was the wonderful innkeeper, so friendly and helpful."
The price is P6,350
P6,931 total
includes taxes & fees
Jul 6 - Jul 7
The Wen Inn formerly Andor Wenneson
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (843)
"The property was clean and neat! It was an excellent stay!"
The price is P6,704
P7,831 total
includes taxes & fees
Jul 4 - Jul 5
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Aspen Suites
Exterior

Aspen Suites

3.0 star property
9.0 out of 10, Wonderful, (604)
"The breakfasts and the additional daily evening menus were very good and appreciated."
The price is P8,174
P10,375 total
includes taxes & fees
Jul 11 - Jul 12
Aspen Suites
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (785)
"Always a great choice!"
The price is P5,582
P6,595 total
includes taxes & fees
Aug 3 - Aug 4
Hotel Indigo Rochester – Mayo Clinic Area by IHG
TownePlace Suites by Marriott Rochester
2 indoor pools

TownePlace Suites by Marriott Rochester

3.0 star property
8.8 out of 10, Excellent, (492)
"The staff was friendly and the breakfast was excellent. "
The price is P5,521
P6,356 total
includes taxes & fees
Jul 17 - Jul 18
TownePlace Suites by Marriott Rochester
The Towers At Kahler Grand Hotel
Front of property

The Towers At Kahler Grand Hotel

4.0 star property
9.4 out of 10, Exceptional, (84)
"Great place to stay if going to Mayo. You don’t have to go outside to get to the buildings at Mayo with the subway level. Food is good for 2 meals a day. There’s room service & deliveries from Instacart if needed for groceries or outside food/beverage source. Personalized concierge service is good. Our stay was 10 days - they accommodated our extended stay flawlessly. My only complaint is the room temperature everywhere; it can be stuffy moving place to place. Take a fan to cool off in...
The price is P22,275
P25,644 total
includes taxes & fees
Jul 12 - Jul 13
The Towers At Kahler Grand Hotel
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

3.0 star property
9.0 out of 10, Wonderful, (722)
"Great location."
The price is P6,935
P7,983 total
includes taxes & fees
Jul 13 - Jul 14
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
AmericInn by Wyndham Rochester
Indoor pool, open 7:00 AM to 11:00 PM, sun loungers

AmericInn by Wyndham Rochester

2.0 star property
8.8 out of 10, Excellent, (1014)
"Nice hotel. Comfy bed. I would stay again. "
The price is P4,262
P4,907 total
includes taxes & fees
Jul 20 - Jul 21
AmericInn by Wyndham Rochester
Big River Escape Grandview Manse
Sundeck

Big River Escape Grandview Manse

3.0 star property
10.0 out of 10, Exceptional, (1)
"It was very roomy and easily accessible. The views were amazing. Would recommend to anyone anytime!!"
Big River Escape Grandview Manse
Kahler Grand Hotel
Indoor pool

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very Good, (1430)
"Great stay!"
Kahler Grand Hotel
Country Trails Inn & Suites
Exterior

Country Trails Inn & Suites

2.0 star property
9.4 out of 10, Exceptional, (72)
"Close to the activities that we were interested in."
The price is P7,126
P7,865 total
includes taxes & fees
Jul 6 - Jul 7
Country Trails Inn & Suites
Econo Lodge Mayo Clinic Area
Lobby

Econo Lodge Mayo Clinic Area

2.0 star property
9.0 out of 10, Wonderful, (688)
"We would stay again."
The price is P3,755
P4,323 total
includes taxes & fees
Aug 3 - Aug 4
Econo Lodge Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Courtyard

Staybridge Suites Rochester - Mayo Clinic Area by IHG

3.0 star property
9.4 out of 10, Exceptional, (367)
"Would definitely stay here again!"
The price is P7,831
P9,128 total
includes taxes & fees
Jul 6 - Jul 7
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Green Gables Inn
Gazebo

Green Gables Inn

2.0 star property
9.6 out of 10, Exceptional, (10)
"Quiet, accessible, very clean. Enjoyed how close it is to downtown. "
The price is P6,591
P7,078 total
includes taxes & fees
Jul 7 - Jul 8
Green Gables Inn
Spark by Hilton Rochester South
1 bedroom, hypo-allergenic bedding, in-room safe, desk

Spark by Hilton Rochester South

3.0 star property
9.4 out of 10, Exceptional, (58)
"Great place will stay again "
The price is P3,930
P4,524 total
includes taxes & fees
Jul 13 - Jul 14
Spark by Hilton Rochester South
Marriott Rochester Mayo Clinic
View from property

Marriott Rochester Mayo Clinic

3.5 star property
8.2 out of 10, Very Good, (505)
"Excellent location for Mayo "
The price is P11,774
P13,555 total
includes taxes & fees
Jul 6 - Jul 7
Marriott Rochester Mayo Clinic
The Plaza Hotel & Suites Winona
Lunch and dinner served, American cuisine

The Plaza Hotel & Suites Winona

3.0 star property
8.8 out of 10, Excellent, (1002)
"Great, convenient place to stay in Winona."
The price is P8,169
P9,119 total
includes taxes & fees
Jul 9 - Jul 10
The Plaza Hotel & Suites Winona
Candlewood Suites Rochester Mayo Clinic Area by IHG
Exterior

Candlewood Suites Rochester Mayo Clinic Area by IHG

2.5 star property
9.4 out of 10, Exceptional, (434)
"Very clean, free parking, coffee shops nearby walking distance, great accommodations for the price. "
The price is P5,690
P6,551 total
includes taxes & fees
Jul 5 - Jul 6
Candlewood Suites Rochester Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1 bedroom, blackout drapes, soundproofing, iron/ironing board

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
8.2 out of 10, Very Good, (637)
"My boyfriend and I absolutely loved this hotel and we will certainly be staying there again if we come to visit"
The price is P5,031
P5,792 total
includes taxes & fees
Jul 13 - Jul 14
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Family-friendly hotels in St. Charles you'll enjoy

The Plaza Hotel & Suites Winona
Lunch and dinner served, American cuisine

The Plaza Hotel & Suites Winona

3.0 star property
8.8 out of 10, Excellent, (1002)
The price is P8,169
P9,119 total
includes taxes & fees
Jul 9 - Jul 10
The Plaza Hotel & Suites Winona

Hotels with a spa in St. Charles may fit your trip

Hilton Rochester Mayo Clinic Area
Lobby

Hilton Rochester Mayo Clinic Area

3.5 star property
9.6 out of 10, Exceptional, (487)
The price is P10,016
P11,531 total
includes taxes & fees
Jul 25 - Jul 26
Hilton Rochester Mayo Clinic Area

Check out cabins in St. Charles

Big River Escape Riverside Cabins
Private kitchen

Big River Escape Riverside Cabins

3.0 star property
9.0 out of 10, Wonderful, (30)
The price is P9,228
P9,736 total
includes taxes & fees
Jul 13 - Jul 14
Big River Escape Riverside Cabins
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles

Frequently asked questions

Where is the best place to stay in St. Charles?

Based on Expedia's traveler preferences, White Valley Motel is a top place to stay in St. Charles. Other good options for your trip to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

Where can I learn more about changing or cancelling my trip to St. Charles?

To access more information about updating your trip to St. Charles or cancelling it, go to https://www.expedia.com/service/.

Where is the best hotel to stay near Whitewater State Park?

White Valley Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 6.4 mi (10.3 km) from Whitewater State Park. Other good choices around the area include Kahler Inn and Suites - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S.

What are some hotels with pools in St. Charles?

Kahler Inn and Suites - Mayo Clinic Area: 3.5-star hotel steps from Mayo Clinic. Offers a snack bar, an indoor pool, and free WiFi. Even Hotel Rochester - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S are a couple of other choices with an onsite pool. View all hotels with pools in St. Charles.

What's the best hotel for staying near Rochester International Airport (RST)?

AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.

What's it like staying in St. Charles?

Visitors can enjoy all that St. Charles has to offer including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 2 hotels and other accommodations to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

A couple of favorite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Check out what more to see and do in Expedia's St. Charles guide.

What's the seasonal weather like in St. Charles?

The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.