Otay Mesa

San Diego


Popular places to visit

Things to do


Top hotels in Otay Mesa

Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4 out of 5
333 W Harbor Dr, San Diego, CA
The price is P11,405 per night from Jun 26 to Jun 27
P11,405
P15,780 total
Jun 26 - Jun 27
includes taxes & fees
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,698 reviews)
"Great property and great service"

Reviewed on Jun 11, 2025

Marriott Marquis San Diego Marina
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4 out of 5
1 Market Pl, San Diego, CA
The price is P11,742 per night from Jun 26 to Jun 27
P11,742
P16,684 total
Jun 26 - Jun 27
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,778 reviews)
"Recently renovated room with great view. & great lighting in the room. Did not like: Self parking was too expensive at $49/night & unable to watch local Padre game in room."

Reviewed on Jun 12, 2025

Manchester Grand Hyatt San Diego
Kings Inn San Diego
Kings Inn San Diego
2.5 out of 5
1333 Hotel Cir S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is P7,997 per night from Jun 15 to Jun 16
P7,997
P9,177 total
Jun 15 - Jun 16
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,256 reviews)
"Room was very clean. It’s close to downtown San Diego. A quick drive."

Reviewed on Jun 12, 2025

Kings Inn San Diego
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is P12,778 per night from Jun 15 to Jun 16
P12,778
P14,687 total
Jun 15 - Jun 16
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,467 reviews)
Great, except….
"Everything was beyond expectations except the incredibly uncomfortable GIANT pillows. Unless you can sleep w basketballs as pillows, call front desk and ask for feather or flatter pillows. Also, the AC is poor. Even on low it blows hard and LOUD! Then, upon reaching set temperature, it instantly ..."

Reviewed on Jun 12, 2025

The Dana on Mission Bay
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown
4 out of 5
601 Pacific Hwy, San Diego, CA
The price is P11,193 per night from Jun 22 to Jun 23
P11,193
P14,551 total
Jun 22 - Jun 23
includes taxes & fees
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,199 reviews)
Nice hotel
"The hotel itself is nice and clean. A short walk to the Seaport Village. Close to Maritime and Embarcadero. The only downside is the parking. No self parking, valet only and it costs $60/night with in and out privileges. Theres a $25 destination that is consumable. The water pressure on the shower ..."

Reviewed on Jun 10, 2025

Embassy Suites by Hilton San Diego Bay Downtown
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is P8,070 per night from Jun 24 to Jun 25
P8,070
P10,986 total
Jun 24 - Jun 25
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,707 reviews)
"This is always a great place to stay. Close to everything. Clean rooms, helpful staff and very accomodating. You can't go wrong stary here...."

Reviewed on Jun 10, 2025

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa

Lake Murray in San Diego

Mid-City

If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Gaslamp Quarter
US Grant Hotel

Downtown San Diego

Seaport Village and Petco Park are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Downtown San Diego
Try the tamale eggs Benedict!

North Park

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

North Park
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy
Default Image

Del Cerro

Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.

Del Cerro

Otay Mesa