Otay Mesa
San Diego
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
Crossing Borders: Tijuana Day Trip from San Diego
San Diego USS Midway with Waterfront Walking Tour
Intro to Mexico Walking Tour: Tijuana Day Trip from San Diego
Tour the buffooner/wine route/port new lobster
Top hotels in Otay Mesa
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Reviewed on Jul 3, 2025
Other neighbourhoods around Otay Mesa
Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Seaport Village and Petco Park are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
Del Cerro
Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.