Smallpox Island
Visit Smallpox Island
Popular places to visit
Lincoln Douglas Square
Stand in the presence of U.S. history, on the spot where Lincoln and Douglas debated as statesmen two years prior to a presidential race that changed everything.
Alton Prison
See the remains of a prison which was built over 150 years ago and which housed Confederate prisoners during the Civil War.
Riverview Park
Explore the great outdoors at Riverview Park, a lovely green space in Alton. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
Piasa Park
Explore the great outdoors at Piasa Park, a lovely green space in Alton. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
National Great Rivers Museum
Next to the wide Mississippi River is a museum filled with activities and displays explaining the history and importance of the river.
Argosy Casino
Why not try your luck with a visit to Argosy Casino during your time in Alton? Visit the shops in this family-friendly area, or simply enjoy its restaurants.
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- Vacations and getaways similar to Smallpox Island
- Hotels Near Smallpox Island, Alton
- Hotels near other Attractions
- Hotel Theme
- Marriott St. Louis Airport
- Hyatt Regency St. Louis at The Arch
- Crowne Plaza St. Louis Airport, an IHG Hotel
- Hollywood Casino & Hotel St. Louis
- Moonrise Hotel
- Drury Plaza Hotel St. Louis at the Arch
- 21C Museum Hotel St Louis
- Clayton Plaza Hotel & Extended Stay
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)