Serra Mesa Hotels near San Diego

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Top Trending Hotels Near Serra Mesa, San Diego

Sycuan Casino Resort
Relax by the resort pool surrounded by palm trees and a pebble bed.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1413)
"Great place to stay beautiful casino! "
Sycuan Casino Resort
Days Inn by Wyndham San Diego-East/El Cajon
Relax in this serene space with a large bed, ocean-inspired artwork, and a cozy reading nook by the window.

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1006)
"Cozy bed, very quiet and convenient"
The price is P6,520
P7,185 total
includes taxes & fees
Aug 17 - Aug 18
Days Inn by Wyndham San Diego-East/El Cajon
Best Western Plus La Mesa San Diego
Relax in the stylish lobby, featuring a reception desk, comfortable seating area, and decorative shelving unit.

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1008)
"Staff was friendly, hotel was clean and breakfast was great"
The price is P7,046
P7,751 total
includes taxes & fees
Aug 17 - Aug 18
Best Western Plus La Mesa San Diego
SpringHill Suites by Marriott Chula Vista Eastlake
Relax by the ocean with a clear view from this pool area, surrounded by lounge chairs and tables under the shade of palm trees.

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (377)
"Great place and location "
The price is P8,808
P9,706 total
includes taxes & fees
Aug 10 - Aug 11
SpringHill Suites by Marriott Chula Vista Eastlake
Ramada by Wyndham San Diego Poway Miramar
Stroll through lush gardens featuring a majestic palm tree and vibrant bird of paradise flowers.

Ramada by Wyndham San Diego Poway Miramar

2.0 star property
7.0 out of 10, Good, (844)
"Our stay went well, and the hotel is a good value"
The price is P5,651
P6,216 total
includes taxes & fees
Aug 17 - Aug 18
Ramada by Wyndham San Diego Poway Miramar
Sonesta ES Suites San Diego - Rancho Bernardo
Compact kitchen area with a dishwasher, microwave, and refrigerator.

Sonesta ES Suites San Diego - Rancho Bernardo

3.0 star property
8.2 out of 10, Very Good, (1006)
"Very nice place for families "
The price is P6,234
P7,103 total
includes taxes & fees
Aug 10 - Aug 11
Sonesta ES Suites San Diego - Rancho Bernardo
Ayres Hotel San Diego South - Chula Vista
Relax in a comfortable seating area surrounded by lush greenery and a bar.

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1085)
"The area was amazing, food & shopping options were right across the hotel which was very convenient. Amenities were great, complimentary breakfast had good options, and staff were friendly. "
The price is P9,977
P10,994 total
includes taxes & fees
Aug 3 - Aug 4
Ayres Hotel San Diego South - Chula Vista
Heritage Inn La Mesa
Relax by the pool surrounded by a deck with comfortable seating and umbrellas.

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1043)
"Familiar stay"
The price is P4,375
P4,824 total
includes taxes & fees
Jul 22 - Jul 23
Heritage Inn La Mesa
La Quinta Inn by Wyndham San Diego - Miramar
Welcome to the hotel's reception area, featuring a central desk with a flat top and a stunning cityscape mural above.

La Quinta Inn by Wyndham San Diego - Miramar

3.0 star property
7.6 out of 10, Good, (1008)
"comfortable bed & clean rooms"
The price is P6,846
P7,869 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn by Wyndham San Diego - Miramar
Lamplighter Inn & Suites at SDSU
Relax by the pool surrounded by lounge chairs and umbrellas, with a lifeguard on duty.

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1214)
"Clean rooms, simple checkin, plenty of parking"
Lamplighter Inn & Suites at SDSU
Best Western Chula Vista/Otay Valley Hotel
Relax in a well-appointed room with a comfortable seating area, desk, and coffee station.

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1460)
"Very nice bed and very quiet y good breakfast in the morning "
The price is P7,243
P7,968 total
includes taxes & fees
Aug 3 - Aug 4
Best Western Chula Vista/Otay Valley Hotel
La Quinta Inn by Wyndham San Diego Chula Vista
Experience the charm of this historic hotel, featuring a striking bell tower and sheltered entrance.

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1305)
"Love the breakfast and convenient location. "
The price is P6,949
P7,644 total
includes taxes & fees
Jul 22 - Jul 23
La Quinta Inn by Wyndham San Diego Chula Vista
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Two single beds with geometric-patterned bedding and a dark headboard, set against a backdrop of white and blue walls.

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1139)
"Great stay"
The price is P4,746
P5,408 total
includes taxes & fees
Aug 4 - Aug 5
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Valli Hi Motel
Relax in a spacious room with a large bed, wooden desk, and comfortable seating area.

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1013)
"Staff was friendly hotel was clean and easy day trips back and forth throughout San Diego area."
Valli Hi Motel
Best Western Americana Inn
Two large beds with white linens and wooden headboards, a flat-screen TV, and a desk with a lamp.

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1116)
"It’s a very nice clean and friendly people in the property"
The price is P7,499
P8,530 total
includes taxes & fees
Jul 29 - Jul 30
Best Western Americana Inn
Chula Vista Inn
Stunning hotel entrance with arched design, surrounded by lush greenery and a palm tree.

Chula Vista Inn

2.5 star property
6.6 out of 10, (1004)
"Nice hotel "
Chula Vista Inn
Hotel Palmeras Chula Vista
Guests can park adjacent to the building, with a covered entrance nearby.

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1779)
"Great rooms ,Awesome staff. And pet friendly!!! "
The price is P4,398
P4,838 total
includes taxes & fees
Jul 28 - Jul 29
Hotel Palmeras Chula Vista
Hercor Hotel - Urban Boutique
Relax in a serene space with a large bed, desk, and comfortable seating area.

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1207)
"Great place to stay!"
The price is P6,037
P6,652 total
includes taxes & fees
Jul 29 - Jul 30
Hercor Hotel - Urban Boutique
Howard Johnson by Wyndham National City/San Diego South
Contemporary bathroom with sleek countertop, white sink, and large mirror.

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.4 out of 10, Good, (1003)
"Enjoyed our stay"
The price is P6,234
P6,870 total
includes taxes & fees
Aug 10 - Aug 11
Howard Johnson by Wyndham National City/San Diego South
SureStay Hotel by Best Western Chula Vista San Diego Bay
Relax by the pool surrounded by palm trees and a city view.

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1460)
"Great place"
The price is P5,920
P6,524 total
includes taxes & fees
Jul 30 - Jul 31
SureStay Hotel by Best Western Chula Vista San Diego Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Belmont Park which includes a garden and rides
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach Park showing a sandy beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter which includes signage, a bar and night scenes
Gaslamp Quarter map

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Handlery Hotel

Handlery Hotel

10/10 Excellent
"We’re still missing our deposit from our last stay. My gf paid for the last night and she hasn’t received her refund from this hotel. "
Jeremy 1-night trip
Posted 10 hours ago
Handlery Hotel

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 35 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.