Serra Mesa Hotels near San Diego

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Jul 18 - Jul 19
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Top Trending Hotels Near Serra Mesa, San Diego

Sycuan Casino Resort
Relax by the resort pool surrounded by palm trees and a pebble bed.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1406)
"Great place to stay beautiful casino! "
Sycuan Casino Resort
Bay Club Hotel & Marina
Enjoy a tranquil marina view from your balcony, complete with a table for two.

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2730)
"Great hotel, wonderful location, comfy room and bedding!"
The price is P8,195
P9,420 total
includes taxes & fees
Aug 18 - Aug 19
Bay Club Hotel & Marina
Best Western San Diego Pacific Beach/Mission Bay
Relax by the pool surrounded by palm trees and a building in the background.

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1240)
"Great place"
The price is P6,222
P7,152 total
includes taxes & fees
Jul 22 - Jul 23
Best Western San Diego Pacific Beach/Mission Bay
Best Western Plus Island Palms Hotel & Marina
Welcome to our lobby, featuring a spacious area with a central counter, pendant lights, and a tropical mural.

Best Western Plus Island Palms Hotel & Marina

3.0 star property
8.8 out of 10, Excellent, (1552)
"Very comfortable beds, gorgeous water view, front desk staff was wonderful. "
The price is P7,257
P8,342 total
includes taxes & fees
Aug 18 - Aug 19
Best Western Plus Island Palms Hotel & Marina
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Grand Central Hotel features a symmetrical facade with evenly spaced windows and a grand arched entrance.

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

4.0 star property
9.2 out of 10, Wonderful, (404)
"Great stay!"
The price is P9,226
P10,679 total
includes taxes & fees
Jul 20 - Jul 21
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Sea Harbor Hotel
Boats docked in a serene marina, offering a tranquil waterfront experience.

Sea Harbor Hotel

2.0 star property
8.6 out of 10, Excellent, (895)
"Would definitely stay there again. ."
The price is P10,628
P11,983 total
includes taxes & fees
Aug 16 - Aug 17
Sea Harbor Hotel
Handlery Hotel
Relax by the resort's large pool surrounded by lounge chairs and umbrellas, set amidst lush palm trees and tropical plants.

Handlery Hotel

3.5 star property
8.2 out of 10, Very Good, (1876)
"Really enjoyed our stay. Great service and very clean"
The price is P6,347
P7,296 total
includes taxes & fees
Jul 22 - Jul 23
Handlery Hotel
Hyatt Regency La Jolla
Relax by the pool surrounded by lounge chairs and umbrellas, with a scenic view of trees in the background.

Hyatt Regency La Jolla

4.0 star property
8.8 out of 10, Excellent, (1010)
"Great hotel/resort!"
The price is P8,195
P11,523 total
includes taxes & fees
Aug 17 - Aug 18
Hyatt Regency La Jolla
Legacy Resort Hotel & Spa
Welcome to our hotel, set amidst beautifully maintained gardens with a clear path leading to the main building.

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2870)
"Great place to stay! "
The price is P8,363
P9,613 total
includes taxes & fees
Aug 6 - Aug 7
Legacy Resort Hotel & Spa
SpringHill Suites by Marriott Chula Vista Eastlake
Relax by the ocean with a clear view from this pool area, surrounded by lounge chairs and tables under the shade of palm trees.

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (377)
"Great place and location "
The price is P8,819
P9,718 total
includes taxes & fees
Aug 10 - Aug 11
SpringHill Suites by Marriott Chula Vista Eastlake
Wyndham Garden San Diego Near SeaWorld
Relax in our spacious lobby with comfortable seating, a central bar, and high ceilings.

Wyndham Garden San Diego Near SeaWorld

3.0 star property
7.2 out of 10, Good, (3909)
"Nice place to stay"
The price is P7,363
P8,464 total
includes taxes & fees
Jul 20 - Jul 21
Wyndham Garden San Diego Near SeaWorld
The Beau Downtown San Diego Gaslamp Quar
Enjoy casual outdoor dining and socializing in this inviting patio area with tables, chairs, and lush greenery.

The Beau Downtown San Diego Gaslamp Quar

3.0 star property
8.8 out of 10, Excellent, (308)
"Great location, friendly staff!"
The price is P8,710
P9,908 total
includes taxes & fees
Jul 20 - Jul 21
The Beau Downtown San Diego Gaslamp Quar
Best Western Plus Marina Gateway Hotel
Two large beds with blue and white bedding, a desk, and a potted plant adorn this stylish room.

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3132)
"This was our second time staying here and we loved it just as much as the first! Such a great hotel, friendly staff and a great location!"
The price is P8,711
P9,599 total
includes taxes & fees
Aug 3 - Aug 4
Best Western Plus Marina Gateway Hotel
Pleasant Inn
Two beds with white and red bedding, a desk, chair, TV, and window with curtains.

Pleasant Inn

2.5 star property
8.4 out of 10, Very Good, (1068)
"near good restaurants "
The price is P5,355
P6,144 total
includes taxes & fees
Aug 11 - Aug 12
Pleasant Inn
Humphreys Half Moon Inn
Relax by the pool surrounded by palm trees and lounge chairs, with umbrellas providing shade.

Humphreys Half Moon Inn

3.5 star property
9.2 out of 10, Wonderful, (2416)
"Great place to stay!!"
The price is P9,226
P11,750 total
includes taxes & fees
Aug 18 - Aug 19
Humphreys Half Moon Inn
The Encinitan Hotel & Suites
Relax by the pool surrounded by lush tropical plants and palm trees, with lounge chairs and umbrellas providing shade.

The Encinitan Hotel & Suites

3.0 star property
8.0 out of 10, Very Good, (1034)
"Great location / family friendly "
The Encinitan Hotel & Suites
Best Western Plus Bayside Inn
Relax in the hotel lobby with a view of the city, featuring a comfortable sofa and a reception desk.

Best Western Plus Bayside Inn

3.0 star property
8.8 out of 10, Excellent, (1001)
"We will definitely stay here again!"
The price is P8,519
P9,860 total
includes taxes & fees
Jul 28 - Jul 29
Best Western Plus Bayside Inn
La Quinta Inn by Wyndham San Diego Chula Vista
Experience the charm of this historic hotel, featuring a striking bell tower and sheltered entrance.

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1301)
"Love the breakfast and convenient location. "
The price is P7,164
P7,881 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn by Wyndham San Diego Chula Vista
Hotel Palmeras Chula Vista
Guests can park adjacent to the building, with a covered entrance nearby.

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1766)
"Great rooms ,Awesome staff. And pet friendly!!! "
The price is P5,306
P5,837 total
includes taxes & fees
Jul 20 - Jul 21
Hotel Palmeras Chula Vista
California Suites Hotel
Stroll through the tranquil corridor, lined with lush greenery and neatly trimmed bushes, leading to a peaceful balcony area.

California Suites Hotel

2.0 star property
7.6 out of 10, Good, (1908)
"Great place not far from downtown nice and quiet lovely pool and jacuzzi and very clean rooms "
California Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Belmont Park which includes a garden and rides
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach Park showing a sandy beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter which includes signage, a bar and night scenes
Gaslamp Quarter map

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Handlery Hotel

Handlery Hotel

10/10 Excellent
"San Diego local here! Always known about the hotel circle but this gem really stood out! I loved how the layout was, there were multiple spread out buildings so it didn’t feel claustrophobic. The property was walkable and had hidden gems on the property. I loved the tiki island vibe! Staff were helpful and friendly. I highly recommend this spot! It’s close to Point Loma, ocean beach, old town, and the shopping mall! All within driving distance. "
Jasmine 2-night trip
Posted 6 hours ago
Handlery Hotel

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 35 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.