Santa Cruz Hotels

Alfonsina Hotel Boutique by Inboccaluppo is a favorite with Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.

Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. See all vacation rentals in Santa Cruz.

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

Based on our traveler reviews, Hostal Killa is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.

Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Novotel Santa Cruz De La Sierra. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.

Buganvillas Hotel Suites & Spa is a favorite 4-star hotel for couples, and features in-room massages and rainfall showerheads. See all romantic hotels in Santa Cruz.

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

Hotel G is a top hotel for people traveling with their pets, and offers a coffee shop and free WiFi for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.

Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.

One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Novotel Santa Cruz De La Sierra and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.

Senses Boutique Hotel is a favorite 3.5-star hotel with our travelers looking for a stylish accommodation, featuring 52 guestrooms, 3 restaurants, and a bar.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Sun Hotel and Yotau All Suites Hotel. View all hotels with pools in Santa Cruz.

Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness center, tennis courts, and a bar. Spend an afternoon at Hotel Spa where you’ll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.

Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 217 hotels and other accommodations to choose from. Find out more about Santa Cruz.

Cultural venues include Cine Center, Ethno-folkloric Museum, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Arenal Park, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.

To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.