Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.

Calle 50

Things to do

Aerial view of the Panama Canal

Panama Canal Half Transit Experience

P8,601
per adult
84% of travellers recommend
Panama Canal Half Transit Experience
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

P8,544
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

P6,135
per adult
90% of travellers recommend
Panama City: Poin Full Package Experience
Slingshot Tour Panama

Slingshot Tour Panama

P6,394
per adult
Slingshot Tour Panama
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

P1,841
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panamá Barcrawl - Old Town Casco Viejo

The Panama Barcrawl - The OG Crawl

P2,867
per adult
94% of travellers recommend
The Panama Barcrawl - The OG Crawl
See all activities in Panama City

Top hotels in Santa Ana

Casco View Apartments
Casco View Apartments
3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
The price is P3,596 per night from 7 Apr to 8 Apr
P3,596
P5,383 total
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3-star condo in Panama City. Enjoy free WiFi, premium bedding, and in-room washers/dryers. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.4/10 Exceptional! (24 reviews)
"Great accommodations. Great view. Great host."

Reviewed on Mar 21, 2025

Casco View Apartments
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is P6,761 per night from 21 Apr to 22 Apr
P6,761
P7,437 total
includes taxes & fees
Apr 21 - Apr 22
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,810 reviews)
Amazing
"Amazing, Buffet the best I've ever experienced"

Reviewed on Apr 2, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is P6,704 per night from 4 May to 5 May
P6,704
P8,312 total
includes taxes & fees
May 4 - May 5
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (2,083 reviews)
"We stayed here when we landed and when we departed Panama due to our flight times. The hotel transportation was very convenient. When we arrived, we called ahead to the hotel to let them know we would be looking for transport. After a series of delays, it was about 1AM when we arrived. We enjoyed ..."

Reviewed on Apr 2, 2025

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is P14,987 per night from 30 Apr to 1 May
P14,987
P14,987 total
includes taxes & fees
Apr 30 - May 1
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,002 reviews)
"WOULD RECOMMEND."

Reviewed on Apr 2, 2025

Dreams Playa Bonita Panama - All Inclusive
Riande Urban Hotel
Riande Urban Hotel
3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
The price is P3,741 per night from 7 Apr to 8 Apr
P3,741
P4,115 total
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
8.6/10 Excellent! (1,005 reviews)
"The location is great. Check in was very smooth and the staff was very polite and helpful. Dinner was great."

Reviewed on Apr 4, 2025

Riande Urban Hotel
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is P10,409 per night from 1 May to 2 May
P10,409
P11,450 total
includes taxes & fees
May 1 - May 2
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,000 reviews)
"Love the staff"

Reviewed on Mar 24, 2025

JW Marriott Panama
See all 1,387 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

San Felipe

If you're spending some time in San Felipe, Metropolitan Cathedral of Panama and Interoceanic Canal Museum are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Metropolitan Cathedral of Panama.

El Chorrillo
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Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Flag of Cerro Ancón, a few notable attractions nearby.

Balboa
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

Santa Ana