Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.
Things to do
From Panama City: Monkey Islands Tour on Gatun Lake
Panama City Visit an Indian town Embera and waterfall with lunch
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Tour to a waterfall and Embera village with lunch included
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Top hotels in Santa Ana
Casco View Apartments
The room was spotless and the decor was beautiful. The location was very convenient and the staff was friendly, in particular Marciello. The only downsides were that there was no hot water in the shower and the air conditioning vented onto the deck, making it really hot to sit on the deck.
Reviewed on Feb 22, 2026
Hotel Riu Plaza Panama
The room smells musty.
Reviewed on Feb 24, 2026
Crowne Plaza Panama Airport by IHG
Staff were pleasant and courteous. The room was clean. Nice pool, lobby bar and restaurant,
Reviewed on Feb 24, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Everything was excelent, thank you for having have a good staid at the hotel 🥰✍️🙏
Reviewed on Feb 24, 2026
Sheraton Grand Panama
The staff was courteous and overall very helpful. The spaces were clean. They had easy access to taxis if you needed them and the breakfast buffet, and restaurants were delicious. We did ask for extra water a few times and it was stated it would be brought up and never was. Other than that, the stay ...
Reviewed on Feb 23, 2026
W Panama
Yes
Reviewed on Feb 23, 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Maracana Stadium.
Calidonia
You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.
Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.
