Photo by Leonardo De Leon

Otay Mesa West Hotels near San Diego

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Otay Mesa West, San Diego

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1416)
"Great place to stay beautiful casino! "
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1008)
"Cozy bed, very quiet and convenient"
The price is P6,520
P7,185 total
includes taxes & fees
Aug 17 - Aug 18
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.8 out of 10, Good, (1004)
"Convenient, one night stay."
The price is P5,948
P6,543 total
includes taxes & fees
Aug 10 - Aug 11
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1010)
"Staff was friendly, hotel was clean and breakfast was great"
The price is P7,046
P7,751 total
includes taxes & fees
Aug 17 - Aug 18
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (377)
"Great place and location "
The price is P8,808
P9,706 total
includes taxes & fees
Aug 10 - Aug 11
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1085)
"The area was amazing, food & shopping options were right across the hotel which was very convenient. Amenities were great, complimentary breakfast had good options, and staff were friendly. "
The price is P9,977
P10,994 total
includes taxes & fees
Aug 3 - Aug 4
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1045)
"Familiar stay"
The price is P4,375
P4,824 total
includes taxes & fees
Jul 28 - Jul 29
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1215)
"Clean rooms, simple checkin, plenty of parking"
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1462)
"Very nice bed and very quiet y good breakfast in the morning "
The price is P7,240
P7,964 total
includes taxes & fees
Aug 4 - Aug 5
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1307)
"Love the breakfast and convenient location. "
The price is P6,949
P7,644 total
includes taxes & fees
Jul 23 - Jul 24
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1141)
"Great stay"
The price is P4,744
P5,405 total
includes taxes & fees
Aug 4 - Aug 5
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1015)
"Staff was friendly hotel was clean and easy day trips back and forth throughout San Diego area."
Valli Hi Motel

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1117)
"It’s a very nice clean and friendly people in the property"
The price is P7,495
P8,526 total
includes taxes & fees
Jul 29 - Jul 30
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.6 out of 10, (1004)
"Nice hotel "
Chula Vista Inn

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1781)
"Great rooms ,Awesome staff. And pet friendly!!! "
The price is P4,398
P4,838 total
includes taxes & fees
Jul 28 - Jul 29
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1208)
"Great place to stay!"
The price is P5,773
P6,362 total
includes taxes & fees
Jul 28 - Jul 29
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.4 out of 10, Good, (1004)
"Enjoyed our stay"
The price is P6,231
P6,866 total
includes taxes & fees
Aug 21 - Aug 22
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1460)
"Great place"
The price is P5,920
P6,524 total
includes taxes & fees
Jul 29 - Jul 30
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (948)
"Great location within walking distance from the places we wanted to visit."
The price is P6,168
P6,955 total
includes taxes & fees
Jul 23 - Jul 24
Berkshire Motor Hotel

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1878)
"Very pleased with this stay."
The price is P6,802
P7,870 total
includes taxes & fees
Aug 20 - Aug 21
The Rambler Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter map

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighborhood that travelers like for its cathedral.

How many hotels can I expect to find in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodations in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.

Where can I learn more about changing or cancelling my trip to Otay Mesa West?

To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.

What is there to do around this San Diego neighborhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.