South Main

Houston

Photo by Hazem Abdul

Popular places to visit

Things to do


Top hotels in South Main

Comfort Suites near Texas Medical Center - NRG Stadium
Comfort Suites near Texas Medical Center - NRG Stadium
2.5 out of 5
1055 Mcnee Rd, Houston, TX
The price is P5,342 per night from Jul 13 to Jul 14
P5,342
P6,250 total
Jul 13 - Jul 14
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (924 reviews)
"Charged me $20 to check in early. Room was ready. Front desk is a joke, sleeping at the desk, I had to wake the dude up"

Reviewed on Jun 22, 2025

Comfort Suites near Texas Medical Center - NRG Stadium
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
The price is P5,829 per night from Jul 1 to Jul 2
P5,829
P6,820 total
Jul 1 - Jul 2
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,456 reviews)
"The check in and out process was very smooth. The hotel was clean and offered what was needed. Overall, the location was nice but at night time there were a lot of homeless people in the area. Additionally, the front desk staff could work on their hospitality."

Reviewed on Jun 23, 2025

Club Quarters Hotel Downtown, Houston
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
The price is P9,098 per night from Jul 13 to Jul 14
P9,098
P10,779 total
Jul 13 - Jul 14
includes taxes & fees
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,323 reviews)
"We really enjoyed being connected to the convention center for an event. Staff was wonderful."

Reviewed on Jun 23, 2025

Hilton Americas-Houston
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4 out of 5
1100 Texas St, Houston, TX
The price is P7,201 per night from Jul 6 to Jul 7
P7,201
P8,602 total
Jul 6 - Jul 7
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,032 reviews)
"Will be staying here again if needing downtown area."

Reviewed on Jun 21, 2025

Magnolia Hotel Houston, A Tribute Portfolio Hotel
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
The price is P5,791 per night from Jul 24 to Jul 25
P5,791
P6,822 total
Jul 24 - Jul 25
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,125 reviews)
"LOCATION WAS EVERYTHING HOTEL WAS CLEAN STAFF SUPER NICE WILL BOOK AGAIN"

Reviewed on Jun 24, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 out of 5
6633 Travis St, Houston, TX
The price is P5,364 per night from Jul 2 to Jul 3
P5,364
P6,343 total
Jul 2 - Jul 3
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,403 reviews)
"The hotel was near MD Anderson where I had an appointment. I was able to walk and find something to eat along the way."

Reviewed on Jun 23, 2025

Hilton Houston Plaza/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

#race

Astrodome

If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Arena and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.

Astrodome
Default Image

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

If you're spending time in South Central Houston, check out sights like Houston Zoo or Children's Museum of Houston and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
Default Image

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

The Galleria

South Main