Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the entertainment choices and acclaimed art scene in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the entertainment choices and lively festivals in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's lively festivals and fascinating museums.
Space Center Houston
Visit the heart of the American space industry in the control centre that put man on the moon.
Things to do
Space Center Houston Admission Ticket
Houston Museum of Natural Sciences: Planetarium Ticket
Houston: Houston Botanic Garden Entry Ticket
Houston City Tour and Downtown Aquarium All Rides Pass
Top hotels in South Main
Reviewed on Apr 17, 2025
Reviewed on Apr 15, 2025
Reviewed on Apr 15, 2025
Reviewed on Apr 16, 2025
Reviewed on Apr 14, 2025
Reviewed on Apr 15, 2025
Other neighbourhoods around South Main
Astrodome
If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Arena and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.
Greater Third Ward
While you're in Greater Third Ward, take in top sights like Fertitta Center or 2209 Dowling Street, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.