Luxury Hotels in Southwest Illinois, Illinois
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Southwest Illinois Luxury Hotels
Top Southwest Illinois Luxury Hotels

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1002)
The price is P27,961
P32,694 total
includes taxes & fees
Jul 20 - Jul 21

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (538)
The price is P32,705
P38,098 total
includes taxes & fees
Jul 20 - Jul 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Reviews in Southwest Illinois
Recent Reviews in Southwest Illinois

Comfort Suites Mount Vernon
5/5 Excellent
"It’s a VERY clean spacious room for family. I stayed at more expensive hotel but it’s not as clean as this one. We will stay there again on the next trip. It’s the BEST choice I made! "
A verified traveler stayed at Comfort Suites Mount Vernon
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotel Theme
- Beach Hotels in Southwest Illinois
- Budget Hotels in Southwest Illinois
- Business Hotels in Southwest Illinois
- Casino Hotels in Southwest Illinois
- Family friendly Hotels in Southwest Illinois
- Golf Hotels in Southwest Illinois
- Hotels near Shopping Areas in Southwest Illinois
- Hotels with Air Conditioning in Southwest Illinois
- Hotels with Balcony in Southwest Illinois
- Hotels with Bars / Lounges in Southwest Illinois
- Hotels with Breakfast in Southwest Illinois
- Hotels with Entertainment in Southwest Illinois
- Hotels with Gyms in Southwest Illinois
- Hotels with Hot Tubs in Southwest Illinois
- Hotels with Internet in Southwest Illinois
- Hotels with Restaurants in Southwest Illinois
- Hotels with Spa in Southwest Illinois
- Hotels with Swimming Pool in Southwest Illinois
- Hotels with Views in Southwest Illinois
- Hotels with Waterparks in Southwest Illinois
- Hotels with WiFi in Southwest Illinois
- Hotels with connecting rooms in Southwest Illinois
- Hotels with free Internet in Southwest Illinois
- Hotels with free breakfast in Southwest Illinois
- Hotels with free parking in Southwest Illinois
- Hotels with free wifi in Southwest Illinois
- Hotels with indoor pool in Southwest Illinois
- Hotels with parking in Southwest Illinois
- Hotels with shuttle in Southwest Illinois
- Hotels with smoking rooms in Southwest Illinois
- Pet friendly Hotels in Southwest Illinois
- Romantic Hotels in Southwest Illinois
More accommodations in Southwest Illinois
- Motels in Illinois
- Vacation Homes in Illinois
- Apartments in Illinois
- Aparthotels in Illinois
- B&B in Illinois
- Condo Rentals in Illinois
- Guest Houses in Illinois
- Resorts in Illinois
- Inns in Illinois
- Villas in Illinois
- Hostels in Illinois
- Cabin Rentals in Illinois
- RV Parks in Illinois
- Lodges in Illinois
Hotels near other Attractions
Most Popular Hotels in Southwest Illinois
- Baymont by Wyndham Marion
- Comfort Suites Fairview Heights
- Drury Inn & Suites St. Louis O'Fallon, IL
- Comfort Suites Mount Vernon
- Super 8 by Wyndham Fairview Heights-St. Louis
- Radisson Hotel Fairview Heights - St. Louis
- Super 8 by Wyndham Troy IL/St. Louis Area
- Baymont by Wyndham O'Fallon St. Louis Area
- Days Inn by Wyndham Troy IL
- Holiday Inn Express & Suites Edwardsville by IHG