Santa Cruz Hotels

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Tonight
Feb 24 - Feb 25
Tomorrow
Feb 25 - Feb 26
This weekend
Feb 28 - Mar 2
Next weekend
Mar 7 - Mar 9

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

Hotel Finca Las Hortensias
Property grounds

Hotel Finca Las Hortensias

3.0 star property
8.2 out of 10, Very Good, (166)
"Front desk service was excellent, the food was delicious and the service from Saul was wonderful. "
The price is P3,062
P3,674 total
includes taxes & fees
Mar 2 - Mar 3
Hotel Finca Las Hortensias
Villa Granada
Terrace/patio

Villa Granada

2.0 star property
9.2 out of 10, Wonderful, (37)
"Very noisy "
The price is P2,022
P2,426 total
includes taxes & fees
Mar 9 - Mar 10
Villa Granada
Verticca Hotel
Premium bedding, down comforters, in-room safe, desk

Verticca Hotel

3.0 star property
9.6 out of 10, Exceptional, (111)
"Excelente servicio de día y noche. Súper amables y limpio "
The price is P6,831
P8,197 total
includes taxes & fees
Feb 25 - Feb 26
Verticca Hotel
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Exterior

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 star property
9.4 out of 10, Exceptional, (574)
"Just a simple and safe walk from airport. They also have vans for transportation to and from hotel. Our room was very clean and our balcony was huge. They also had a good selection at their breakfast buffet. And offer 24/7 room service which we enjoyed. Would definitely recommend "
The price is P6,080
P7,296 total
includes taxes & fees
Mar 9 - Mar 10
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Fiesta Inn Ecatepec
Indoor pool

Fiesta Inn Ecatepec

3.5 star property
8.8 out of 10, Excellent, (659)
"Thank you. "
The price is P5,157
P6,189 total
includes taxes & fees
Feb 28 - Mar 1
Fiesta Inn Ecatepec
Hotel Vía la Villa
Interior

Hotel Vía la Villa

2.5 star property
7.8 out of 10, Good, (295)
"This is a hidden gem. Low price, cleanliness, modern, good staff, what more can you ask for. I've stayed at this hotel 2 times now and it has been great. I didn't expect anything luxurious but what I did expect was a clean and convenient option and they exceeded. Thank you so much for your service."
The price is P2,070
P2,473 total
includes taxes & fees
Mar 10 - Mar 11
Hotel Vía la Villa
City Express by Marriott Ciudad de México La Villa
Lobby lounge

City Express by Marriott Ciudad de México La Villa

3.0 star property
8.8 out of 10, Excellent, (841)
"The staff were very good, breakfast was so so, next to a big grocery store chain. Walkable to Our Lady of Guadalupe Shrine. Less than $10 for uber from airport. Big room, clean. "
The price is P3,433
P4,102 total
includes taxes & fees
Mar 3 - Mar 4
City Express by Marriott Ciudad de México La Villa
Gran Hotel Villa de Madrid
Lobby sitting area

Gran Hotel Villa de Madrid

3.5 star property
8.0 out of 10, Very Good, (322)
"It was a big space and was convenient to the basilica "
The price is P2,849
P3,405 total
includes taxes & fees
Feb 25 - Feb 26
Gran Hotel Villa de Madrid
Hotel Piet
Snack bar

Hotel Piet

2.0 star property
7.0 out of 10, Good, (71)
"The property is an 'hourly, adult-only' hotel. It is Ok for solo traveller like myself. The property is old and not well kept but is one of the cheapest accomodations I could find. The property is kept to the best possible standards by the staff who are very engaged and polite. Antonio and Valentina are the names of the staff who try to accommodate your needs but the hotel is in a normal, poorer part of the city and dining options around are limited but available. However, if your aim is to just...
The price is P831
P993 total
includes taxes & fees
Feb 25 - Feb 26
Hotel Piet
Gran Hotel Panorama
Interior entrance

Gran Hotel Panorama

3.0 star property
8.2 out of 10, Very Good, (859)
"Decent hotel for the price. Not in the safest area but as long as you just take an Uber or taxi to get to your destination: you will be fine. No A/C but hotel and room was not hot. Hotel does provide a fan. "
The price is P1,092
P1,305 total
includes taxes & fees
Feb 25 - Feb 26
Gran Hotel Panorama
Holiday Inn Express Mexico Basilica by IHG
Premium bedding, in-room safe, desk, blackout drapes

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
9.2 out of 10, Wonderful, (1003)
"I loved my stay here. Super clean and friendly."
The price is P3,581
P4,279 total
includes taxes & fees
Mar 4 - Mar 5
Holiday Inn Express Mexico Basilica by IHG
Hotel Brasilia
Terrace/patio

Hotel Brasilia

3.0 star property
9.0 out of 10, Wonderful, (1004)
"People were very courteous and respectful, rooms very neat and clean "
The price is P3,444
P4,115 total
includes taxes & fees
Mar 3 - Mar 4
Hotel Brasilia
Mala Vecindad Centro Historico
Rooftop pool

Mala Vecindad Centro Historico

3.0 star property
8.6 out of 10, Excellent, (48)
"Buen lugar, cumple para estadías breves. Si te gusta la cerveza está bueno, te regalan dos y el desayuno está incluido. El entorno es feo, pero siempre hay que andar con cuidado. "
The price is P2,798
P3,343 total
includes taxes & fees
Feb 27 - Feb 28
Mala Vecindad Centro Historico
Hotel MX lagunilla
Front of property

Hotel MX lagunilla

3.5 star property
8.2 out of 10, Very Good, (347)
"A great no frills hotel, clean with a great traditional breakfast(no powdered eggs). Great location to the historic district, metro and places to eat. Free and safe parking in their garage a bonus. "
The price is P1,960
P2,342 total
includes taxes & fees
Mar 24 - Mar 25
Hotel MX lagunilla
City Express by Marriott Ciudad De México La Raza
Exterior

City Express by Marriott Ciudad De México La Raza

3.0 star property
8.8 out of 10, Excellent, (855)
"Clean hotel"
The price is P3,884
P4,642 total
includes taxes & fees
Mar 1 - Mar 2
City Express by Marriott Ciudad De México La Raza
Kali La Raza Mexico City
Front of property

Kali La Raza Mexico City

2.5 star property
9.8 out of 10, Exceptional, (10)
"Really great hotel. The lift doesn't work but we changed floors. The place is so clean. I don't like the breakfast but I'm Scottish and it's Mexican and my wife loved it Bed very comfortable. Great tv and the shower is exceptional. Just across the road you get the bus to take you to the main part. Great staff and very helpful . We booked an extra two nights because the place is great. "
The price is P2,939
P3,512 total
includes taxes & fees
Feb 25 - Feb 26
Kali La Raza Mexico City
Downtown Treasure Place
Bathroom

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (513)
"Really nice and calm place to sleep "
The price is P1,520
P1,840 total
includes taxes & fees
Feb 25 - Feb 26
Downtown Treasure Place
One Ciudad de Mexico La Raza
Exterior

One Ciudad de Mexico La Raza

3.0 star property
8.6 out of 10, Excellent, (740)
"Manchas en la alfombra y la comida no fue tan rica"
The price is P3,593
P4,293 total
includes taxes & fees
Feb 27 - Feb 28
One Ciudad de Mexico La Raza
Hotel Dharma
Property grounds

Hotel Dharma

3.0 star property
8.0 out of 10, Very Good, (342)
"Staff friendly and place clean and quiet."
The price is P1,702
P2,034 total
includes taxes & fees
Feb 25 - Feb 26
Hotel Dharma
Hotel Lepanto Reforma
In-room safe, desk, laptop workspace, blackout drapes

Hotel Lepanto Reforma

3.0 star property
8.4 out of 10, Very Good, (540)
"Nos encantó hospedarnos aquí el personal es lo máximo super recomendado y nos volveremos a quedar aquí "
The price is P3,320
P3,967 total
includes taxes & fees
Mar 4 - Mar 5
Hotel Lepanto Reforma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Cruz
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Cruz

Venture to Hacienda La Concepcion and National Museum of the Viceroyalty—just two of the sights around Santa Cruz.

See all hotels in Santa Cruz

Frequently asked questions

Where is the best place for a stay in Santa Cruz?

Located 18.9 mi (30.4 km) from the heart of Santa Cruz, InterContinental Presidente Mexico City by IHG is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Hyatt Regency Mexico City and Hotel Polanco. See all available top hotels, or vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about changing or cancelling your trip to Santa Cruz, head over to our customer service page.

What are some accommodations with pools in Santa Cruz?

Hotel Finca Las Hortensias: Features free parking, an outdoor pool, and free WiFi. Hyatt Regency Mexico City and Fiesta Americana México Toreo are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Hotel Finca Las Hortensias is a top spa hotel featuring a restaurant and a bar.

What is staying in Santa Cruz like?

Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. There are 1636 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty, and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually April and May with an average temp of 64°F, while the coldest months are January and December with an average of 57°F. The rainiest months in Santa Cruz are August, July, September, and June, with each month seeing an average of 7 inches of rainfall.