Photo by Dr__Vlad

O Brien Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jul 13 - Jul 14
Tomorrow
Jul 14 - Jul 15
Next weekend
Jul 18 - Jul 20
In two weeks
Jul 25 - Jul 27

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending O Brien hotels

Best Western Plus Lake City
Relax in this inviting living area with a sofa, coffee table, and ottoman, plus a staircase leading to an upper level.

Best Western Plus Lake City

2.5 star property
9.2 out of 10, Wonderful, (1010)
"This property was absolutely great, this was the best stay we had our entire trip"
The price is P4,778
P5,375 total
includes taxes & fees
Jul 20 - Jul 21
Best Western Plus Lake City
TownePlace Suites by Marriott Lake City
Relax in our spacious lobby with a central seating area, reception desk, and large window offering a view of the outdoors.

TownePlace Suites by Marriott Lake City

3.0 star property
9.8 out of 10, Exceptional, (86)
"The hotel, staff and amenities are all excellent. "
The price is P7,004
P7,880 total
includes taxes & fees
Jul 20 - Jul 21
TownePlace Suites by Marriott Lake City
Cindys Motel
Relax in a serene outdoor space surrounded by lush greenery and traditional architecture.

Cindys Motel

2.5 star property
9.0 out of 10, Wonderful, (114)
"Clean rooms, good price and easy check-in."
Cindys Motel
Regal Inn
Relax in a spacious room with a large bed, wall-mounted reading lamps, and a blue accent wall.

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (513)
"Great staff great stay"
The price is P3,504
P3,942 total
includes taxes & fees
Jul 27 - Jul 28
Regal Inn
Holiday Inn & Suites Lake City by IHG
Relax in the inviting lobby area with comfortable seating and a beautiful artwork on the wall.

Holiday Inn & Suites Lake City by IHG

3.0 star property
8.6 out of 10, Excellent, (1003)
" Nice place"
The price is P5,366
P6,037 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn & Suites Lake City by IHG
Hampton Inn & Suites Alachua I-75
Experience the hotel's welcoming lobby, featuring a long reception desk, comfortable seating area, and stylish decor.

Hampton Inn & Suites Alachua I-75

2.5 star property
9.4 out of 10, Exceptional, (426)
"Great pool also"
The price is P6,428
P7,232 total
includes taxes & fees
Aug 4 - Aug 5
Hampton Inn & Suites Alachua I-75
Vista Verde Farm Retreat
1 bedroom, laptop workspace, free WiFi, bed sheets

Vista Verde Farm Retreat

2.0 star property
9.8 out of 10, Exceptional, (6)
"This is my second time staying on this property and I love it "
The price is P6,439
P11,172 total
includes taxes & fees
Jul 15 - Jul 16
Vista Verde Farm Retreat
Postcard Cabins Gilchrist Springs
Situated in a wooded area, this cabin offers a cozy outdoor space with a deck, metal table, and chairs, as well as a fire pit.

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (46)
"the cabin was amazing, great amenities i would recommend!!"
The price is P7,287
P10,190 total
includes taxes & fees
Jul 15 - Jul 16
Postcard Cabins Gilchrist Springs
Courtyard By Marriott Lake City
Relax by the fire pit in this outdoor seating area, surrounded by comfortable wicker chairs.

Courtyard By Marriott Lake City

3.0 star property
9.6 out of 10, Exceptional, (108)
"Clean, great service and nice location "
The price is P5,931
P6,672 total
includes taxes & fees
Jul 20 - Jul 21
Courtyard By Marriott Lake City
Fairfield Inn & Suites Lake City
Welcome to our lobby, featuring a central reception desk, a round sofa, and a leather armchair.

Fairfield Inn & Suites Lake City

2.5 star property
9.2 out of 10, Wonderful, (107)
"The staff was friendly and helpful."
The price is P5,592
P6,291 total
includes taxes & fees
Jul 15 - Jul 16
Fairfield Inn & Suites Lake City
La Quinta Inn & Suite by Wyndham Lake City
La Quinta offers a sleek, symmetrical facade with a covered entrance and beautifully maintained grounds.

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1012)
"Location clean and a lot of restaurants near ,"
The price is P5,541
P6,234 total
includes taxes & fees
Jul 15 - Jul 16
La Quinta Inn & Suite by Wyndham Lake City
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Welcome to our hotel, featuring a grand entrance with a covered area and stone pillars.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.4 out of 10, Exceptional, (1010)
"Really enjoyed our stay! "
The price is P4,801
P5,401 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
The Blanche
Hotel Blanche features a classic two-story facade with a prominent balcony and arched windows.

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (139)
"Beautiful hotel! Elegant, classy. Loved it! "
The Blanche
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
Enjoy a wide selection of breakfast options at our buffet, featuring cheese omelets and sausages.

Holiday Inn Express Hotel & Suites LIVE OAK by IHG

2.5 star property
8.4 out of 10, Very Good, (717)
"The room was perfect and the staff very accommodating!"
The price is P6,281
P6,909 total
includes taxes & fees
Jul 16 - Jul 17
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
BlueGem Motel
Welcome to our reception area, where friendly staff are available to assist with your stay.

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (357)
"The property is very much upgraded from the prior owner years ago. The grounds and room were well cared for. "
The price is P5,879
P6,614 total
includes taxes & fees
Jul 15 - Jul 16
BlueGem Motel
Home2 Suites by Hilton Lake City
Relax in a serene outdoor space surrounded by lush greenery and a cozy fire pit.

Home2 Suites by Hilton Lake City

3.0 star property
9.4 out of 10, Exceptional, (685)
"The hotel was very clean and updated. Would definitely recommend and stay here again. "
The price is P6,319
P7,108 total
includes taxes & fees
Jul 20 - Jul 21
Home2 Suites by Hilton Lake City
Comfort Suites Lake City
Welcome to our hotel lobby, featuring a reception area, comfortable seating, and a flat-screen TV.

Comfort Suites Lake City

2.5 star property
9.6 out of 10, Exceptional, (1003)
"The stay was great "
The price is P5,497
P6,184 total
includes taxes & fees
Jul 20 - Jul 21
Comfort Suites Lake City
Tru by Hilton Lake City
Relax in style with a variety of seating options and a cozy fire pit.

Tru by Hilton Lake City

2.5 star property
9.2 out of 10, Wonderful, (1005)
"I would stay again."
The price is P5,592
P6,291 total
includes taxes & fees
Jul 15 - Jul 16
Tru by Hilton Lake City
Suwannee River Rendezvous
Enjoy a peaceful retreat in this secluded cabin surrounded by trees, with a balcony and outdoor dining area.

Suwannee River Rendezvous

2.5 star property
8.4 out of 10, Very Good, (15)
"Great view, loved the spring!"
The price is P1,525
P2,442 total
includes taxes & fees
Jul 15 - Jul 16
Suwannee River Rendezvous
Hampton Inn & Suites Lake City
Relax in the stylish lobby with a round table and two comfortable chairs, a flat-screen TV, and framed artwork on the walls.

Hampton Inn & Suites Lake City

2.5 star property
9.4 out of 10, Exceptional, (981)
"Nice stay"
The price is P5,257
P5,914 total
includes taxes & fees
Jul 20 - Jul 21
Hampton Inn & Suites Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

See all hotels in O Brien
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Frequently asked questions

Where is the best place to stay in O Brien?

La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool, and free self parking. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Best Western Plus Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.