Photo by Dr__Vlad
All hotels in O Brien, Florida
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in O Brien, Florida
We have found 296 O Brien Hotels
- La Quinta Inn & Suite by Wyndham Lake City
- Americas Best Value Inn Lake City
- Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel
- Best Western Plus Lake City
- Days Inn by Wyndham Lake City I-75
- Comfort Suites Lake City
- Hampton Inn & Suites Lake City
- Home2 Suites by Hilton Lake City
- Holiday Inn & Suites Lake City, an IHG Hotel
- Days Inn by Wyndham Lake City I-10
- Quality Inn Lake City
- Quality Inn & Suites Live Oak I-10 Exit 283
- Quality Inn White Springs Suwanee
- Holiday Inn Express Hotel & Suites LIVE OAK, an IHG Hotel
- Regal Inn
- Gateway Inn
- Courtyard By Marriott Lake City
- Grady House Bed & Breakfast
- Guest Inn
- Jasmine Garden Inn
Let Expedia take you to the best Hotels in O Brien. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.