East Prairie Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jul 15 - Jul 16
Tomorrow
Jul 16 - Jul 17
This weekend
Jul 18 - Jul 20
Next weekend
Jul 25 - Jul 27

Vacation Rentals in East Prairie

Boat Dock on Reelfoot Lake: Tiptonville Retreat
Interior

Boat Dock on Reelfoot Lake: Tiptonville Retreat

3.0 star property
Boat Dock on Reelfoot Lake: Tiptonville Retreat
Gloria's on Exchange
Private kitchen

Gloria's on Exchange

3.5 star property
10.0 out of 10, Exceptional, (2)
"Love love love Gloria’s and love Julie and David they are the best hosts."
Gloria's on Exchange
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

Can I find a vacation rental in East Prairie?

Yes, you can find vacation rentals near the most popular sights in East Prairie, or you can select a more secluded option if you're looking for a relaxing stay.

What can I see and do in East Prairie?

Big Oak Tree State Park and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Sikeston Depot Museum and Columbus-Belmont State Park.

What are vacation rentals like in East Prairie?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in East Prairie. Vacation rentals feature extras like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family trips.