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Check prices for these dates

Next weekend
Aug 8 - Aug 10
In two weeks
Aug 15 - Aug 17
In one month
Aug 29 - Aug 31
In two months
Sep 26 - Sep 28

Featured Villas in Duck Key

Waterfront Luxury Villa With Sunset Views And Boat Slip 3 Bedroom Villa by RedAwning
Relax on the ocean-view deck with a round table, two chairs, and a cushioned bench.

Waterfront Luxury Villa With Sunset Views And Boat Slip 3 Bedroom Villa by RedAwning

3.0 star property
Waterfront Luxury Villa With Sunset Views And Boat Slip 3 Bedroom Villa by RedAwning
Turtle Nest Estate in Islamorada
Relax on the beachfront deck with a pool and lounge chairs, surrounded by palm trees and a white fence.

Turtle Nest Estate in Islamorada

2.0 star property
Turtle Nest Estate in Islamorada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Duck Key Hotel Reviews

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent
"Very good"
Isabel 3-night trip
Posted 2 days ago
Tranquility Bay Beachfront Hotel and Resort

Frequently asked questions

How much do villas in Duck Key cost?
Villas in Duck Key range between and per night. These stays provide the privacy of your own space at a price that won't stretch the budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many villas are there in Duck Key?
Take your pick of 2 villas in Duck Key. Whether you're taking a trip with the kids or organizing a weekend escape with your besties, Expedia will help you find the perfect space for your squad.
Are there any family-friendly villas in Duck Key?
If you're planning a trip to Duck Key and need a family-friendly villa, consider Waterfront Luxury Villa - 14 - - 3 Bedroom Townhouse. This 3-star property includes conveniences like a barbecue grill and an oven. Duck Key has lots of family-friendly attractions to explore that'll keep the kids entertained. Coco Plum Beach and Florida Keys Aquarium Encounters promise a fun day out for both young and old.