Luxury Hotels in Destin, Florida

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Destin Luxury Hotels

Top Destin Luxury Hotels

Capitano 7 Bedroom Holiday Home by Five Star Properties
Enjoy breathtaking ocean views from this spacious balcony with a railing and doors leading to the interior.

Capitano 7 Bedroom Holiday Home by Five Star Properties

5.0 star property
Capitano 7 Bedroom Holiday Home by Five Star Properties
Caribbean Queen 5 Bedroom Holiday Home by Five Star Properties
Experience the grandeur of this elegant space with a high ceiling and large chandelier, surrounded by doorways leading to other areas.

Caribbean Queen 5 Bedroom Holiday Home by Five Star Properties

4.5 star property
Caribbean Queen 5 Bedroom Holiday Home by Five Star Properties
Destination Fun 9 Bedroom Holiday Home by Five Star Properties
Enjoy cooking in this well-equipped kitchen with a large island, oven, and microwave.

Destination Fun 9 Bedroom Holiday Home by Five Star Properties

4.5 star property
Destination Fun 9 Bedroom Holiday Home by Five Star Properties
Just the Ticket 4 Bedroom Holiday Home by Five Star Properties
Guests can enjoy access to the beach from this resort.

Just the Ticket 4 Bedroom Holiday Home by Five Star Properties

4.5 star property
Just the Ticket 4 Bedroom Holiday Home by Five Star Properties
Mermaid Vista 5 Bedroom Holiday Home by Five Star Properties
Outdoor pool

Mermaid Vista 5 Bedroom Holiday Home by Five Star Properties

4.5 star property
Mermaid Vista 5 Bedroom Holiday Home by Five Star Properties
Millenia 7 Bedroom Holiday Home by Five Star Properties
Stunning staircase leads to an upper level, flanked by doors and a window with shutters.

Millenia 7 Bedroom Holiday Home by Five Star Properties

5.0 star property
Millenia 7 Bedroom Holiday Home by Five Star Properties
Ocean Paradise 4 Bedroom Holiday Home by Five Star Properties
Enjoy breathtaking ocean views from the rooftop pool, surrounded by a low wall and glass balustrade.

Ocean Paradise 4 Bedroom Holiday Home by Five Star Properties

4.5 star property
Ocean Paradise 4 Bedroom Holiday Home by Five Star Properties
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
Relax by the inviting pool and enjoy the expansive patio with comfortable seating and a scenic view.

Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties

5.0 star property
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
Sea E O 11 Bedroom Holiday Home by Five Star Properties
Outdoor pool

Sea E O 11 Bedroom Holiday Home by Five Star Properties

4.5 star property
Sea E O 11 Bedroom Holiday Home by Five Star Properties
Son Kissed 4 Bedroom Holiday Home by Five Star Properties
Hotel features a two-story design with a balcony on the upper floor, offering outdoor seating and a glass entrance.

Son Kissed 4 Bedroom Holiday Home by Five Star Properties

4.5 star property
Son Kissed 4 Bedroom Holiday Home by Five Star Properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Destin?
Known for its beaches and shopping, Destin also has some interesting things to see and do including Destin Beaches, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Destin?
The Henderson Beach Resort & Spa is a luxury resort with a private beach and 4 restaurants, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels are there in Destin?
Lie in the lap of luxury during your getaway to Destin in one of Expedia's 10 luxury hotels.
When can I expect good weather in Destin?
Planning for the weather is an important factor for making your trip to Destin a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 82°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Destin are August, July, December, and June, with each month seeing an average of 7 inches of rainfall.
What's there to see and do in Destin?
Experience Destin with a stop at Destin Beaches, Big Kahuna's Water and Adventure Park, and Morgan Sports Center. If you have a little extra time during your trip, you might want to make a stop at Henderson Beach and Henderson Beach State Park.