Depew Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Depew hotels

M Hotel Buffalo

3.5 star property
7.4 out of 10, Good, (1654)
"Very nice for couples nights to stay. "
The price is P5,577
P6,344 total
includes taxes & fees
Jul 14 - Jul 15
M Hotel Buffalo

Comfort Inn University

2.5 star property
8.0 out of 10, Very Good, (1025)
"We enjoyed staying at the hotel. Breakfast was good and complimentary coffee was available all the time. Rooms were pretty clean and staffs were very nice."
The price is P6,907
P7,857 total
includes taxes & fees
Jul 13 - Jul 14
Comfort Inn University

Lockport Inn & Suites

2.0 star property
9.2 out of 10, Wonderful, (1009)
"Price, staff, gardens all great"
The price is P5,580
P6,305 total
includes taxes & fees
Jul 13 - Jul 14
Lockport Inn & Suites

Sleep Inn

2.5 star property
8.8 out of 10, Excellent, (1095)
"Always stay here when I’m in town. "
The price is P5,941
P6,758 total
includes taxes & fees
Jul 23 - Jul 24
Sleep Inn

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 star property
8.0 out of 10, Very Good, (1372)
"Great location, staff was very nice, and the rooms were nice and clean."
The price is P5,896
P6,707 total
includes taxes & fees
Jul 20 - Jul 21
Hyatt Regency Buffalo / Hotel and Conference Center

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3.0 star property
8.4 out of 10, Very Good, (1858)
"Nice place to stay at"
The price is P6,229
P7,085 total
includes taxes & fees
Aug 5 - Aug 6
La Quinta Inn & Suites by Wyndham Buffalo Amherst

Hyatt Place Buffalo/Amherst

3.0 star property
9.0 out of 10, Wonderful, (1032)
"Great stay . Recommended and will come back to stay here "
The price is P11,327
P12,885 total
includes taxes & fees
Jul 22 - Jul 23
Hyatt Place Buffalo/Amherst

Lockport Hotel

2.5 star property
7.2 out of 10, Good, (207)
"very nice staff"
The price is P5,326
P6,019 total
includes taxes & fees
Jul 14 - Jul 15
Lockport Hotel

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 star property
8.8 out of 10, Excellent, (1251)
"Great place to stay with family and friends "
The price is P8,433
P9,593 total
includes taxes & fees
Jul 16 - Jul 17
Holiday Inn Express Grand Island - Niagara Falls by IHG

Fairbridge Inn Express Buffalo Airport Williamsville

2.0 star property
4.6 out of 10, (1000)
"Hotel rooms are good, 10-12 min drive from downtown. "
The price is P3,572
P4,063 total
includes taxes & fees
Jul 22 - Jul 23
Fairbridge Inn Express Buffalo Airport Williamsville

Sleep Inn & Suites Buffalo Airport

2.5 star property
8.0 out of 10, Very Good, (1610)
"It is adjacent to the Buffalo airport so very convenient for stays when we arrive late or are leaving early from that airport."
The price is P6,420
P7,302 total
includes taxes & fees
Jul 23 - Jul 24
Sleep Inn & Suites Buffalo Airport

Garden Place Hotel

3.5 star property
7.8 out of 10, Good, (1752)
"We enjoyed our stay."
The price is P6,327
P7,197 total
includes taxes & fees
Jul 10 - Jul 11
Garden Place Hotel

Best Western Galleria Inn & Suites

2.5 star property
6.6 out of 10, (1000)
"Great location, clean room and good breakfast, we would definitely stay here again. "
The price is P6,023
P6,851 total
includes taxes & fees
Jul 13 - Jul 14
Best Western Galleria Inn & Suites

Wyndham Garden Buffalo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1482)
"Very comfortable beds, large rooms, impressive breakfast!"
The price is P7,952
P9,046 total
includes taxes & fees
Jul 14 - Jul 15
Wyndham Garden Buffalo Downtown

DoubleTree by Hilton Hotel Buffalo - Amherst

4.0 star property
7.8 out of 10, Good, (1006)
"Hotel and room were very clean. Staff was friendly and the bed/pillows were very comfortable. "
The price is P8,144
P9,264 total
includes taxes & fees
Jul 13 - Jul 14
DoubleTree by Hilton Hotel Buffalo - Amherst

Extended Stay America Suites - Buffalo - Airport

2.5 star property
7.4 out of 10, Good, (707)
"Good place to stay"
The price is P4,844
P5,510 total
includes taxes & fees
Jul 20 - Jul 21
Extended Stay America Suites - Buffalo - Airport

Holiday Inn Express Cheektowaga North East by IHG

2.5 star property
8.4 out of 10, Very Good, (1015)
"Great place to stay. Close to the airport and very clean. Would stay here again. "
The price is P5,916
P6,730 total
includes taxes & fees
Aug 3 - Aug 4
Holiday Inn Express Cheektowaga North East by IHG

Hotel at the Lafayette Trademark Collection by Wyndham

3.5 star property
8.6 out of 10, Excellent, (1001)
"The staff was very friendly."
The price is P8,962
P10,194 total
includes taxes & fees
Jul 23 - Jul 24
Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Airport Hotel

3.0 star property
8.0 out of 10, Very Good, (2522)
"The hotel has the friendliest staff and it was peaceful and quiet."
Buffalo Airport Hotel

La Quinta Inn by Wyndham Buffalo Airport

3.0 star property
7.8 out of 10, Good, (1241)
"My fav place to stay with my boyfriend."
The price is P5,638
P6,413 total
includes taxes & fees
Jul 21 - Jul 22
La Quinta Inn by Wyndham Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Depew

Escape to romantic Depew! Enjoy its food, sports, and waterfalls.

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Holiday Inn Express Grand Island - Niagara Falls by IHG and Hyatt Regency Buffalo / Hotel and Conference Center. See all available top hotels, or vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

Where can I learn more about changing or cancelling my trip to Depew?

For more information about picking new dates or cancelling your trip to Depew, click here.

What's the best budget-friendly hotel in Depew?

Based on our traveler reviews, Pink Fountain Motor Inn is a top choice for a less expensive stay. View all budget hotels in Depew.

What's the best hotel for a couple going to Depew?

Pink Fountain Motor Inn is a favorite property for couples, and features cable TV and free WiFi. See all romantic hotels in Depew.

What are some accommodations with pools in Depew?

M Hotel Buffalo: Hotel, 6-minute walk from Walden Galleria Mall. Features buffet, an indoor pool, and free self parking. Holiday Inn Express Grand Island - Niagara Falls by IHG and Hyatt Regency Buffalo / Hotel and Conference Center are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.

What is the best spa hotel in Depew?

Pink Fountain Motor Inn is a top spa hotel with 14 rooms, free WiFi, and free self parking. Kick back and relax in the spa tub.

What's the best place to stay near Buffalo Niagara International Airport (BUF)?

Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodations to choose from. Find out more about Depew.

What are the top places to visit in Depew?

Places to visit in the wider area include Walden Galleria Mall, Samuel’s Grande Manor, and Glen Falls. You'll also find Buffalo Central Terminal and Broadway Market in the area. Check out what more to see and do in Expedia's Depew guide.

How should I get around Depew?

To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the weather like in Depew?

The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Depew are January, March, February, and December, with each month seeing an average of 17 inches of snowfall.