Defiance Hotels

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Defiance hotel prices

Tonight
Nov 26 - Nov 27
Tomorrow night
Nov 27 - Nov 28
This weekend
Nov 29 - Dec 1
Next weekend
Dec 6 - Dec 8

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Defiance hotels

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Exterior

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (676)
"Quiet & Staff very helpful & polite. "
The price is P6,806
P8,153 total
includes taxes & fees
Dec 1 - Dec 2
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Baymont by Wyndham Warrenton
Exterior

Baymont by Wyndham Warrenton

2.5 star property
7.2 out of 10, Good, (879)
"Friendly staff . quick check in , clean , good breakfast (many choices)."
The price is P4,506
P5,158 total
includes taxes & fees
Dec 18 - Dec 19
Baymont by Wyndham Warrenton
Quality Inn
Lobby

Quality Inn

2.5 star property
8.2 out of 10, Very Good, (682)
"Very friendly and clean, nice people good value"
The price is P4,712
P5,323 total
includes taxes & fees
Dec 27 - Dec 28
Quality Inn
Economy Inn Wentzville
Lobby

Economy Inn Wentzville

2.0 star property
6.4 out of 10, (394)
"All good "
The price is P4,130
P4,685 total
includes taxes & fees
Nov 27 - Nov 28
Economy Inn Wentzville
Best Western Plus Washington Hotel
Lobby

Best Western Plus Washington Hotel

2.5 star property
9.0 out of 10, Wonderful, (507)
"The staff were very friendly, professional and helpful at check in. We are meeting up with other family members and the staff went out of their way to accommodate our group."
The price is P7,599
P8,651 total
includes taxes & fees
Dec 5 - Dec 6
Best Western Plus Washington Hotel
Super 8 by Wyndham Warrenton
In-room safe, desk, laptop workspace, blackout drapes

Super 8 by Wyndham Warrenton

2.0 star property
7.4 out of 10, Good, (507)
"We stayed on the weekend of Diwali (the beginning of the Hindu fiscal year), so we understood the hotel was short staffed due to the celebration. On our 3rd attempt at a clean room, we got one. The woman working at check in was very kind. Later that evening when we returned, our TV didn't work. Another lady at the front desk came up and called the owner who walked her through fixing it. The room was clean, the beds were comfortable, and we slept well. The next morning my biggest issue was there...
The price is P3,244
P3,714 total
includes taxes & fees
Dec 20 - Dec 21
Super 8 by Wyndham Warrenton
Hampton Inn St. Louis Wentzville
Exterior

Hampton Inn St. Louis Wentzville

2.5 star property
9.0 out of 10, Wonderful, (554)
"Very easy check in process. A lot of the parking was in front of the hotel which in my opinion is amazing. The young lady I dealt with during check in was very friendly and easy to work with. "
The price is P7,973
P9,125 total
includes taxes & fees
Dec 8 - Dec 9
Hampton Inn St. Louis Wentzville
Fairfield Inn & Suites Wentzville
Reception

Fairfield Inn & Suites Wentzville

2.5 star property
9.0 out of 10, Wonderful, (542)
"The staff was very helpful. I had a family emergency and couldn't stay the following night. Booked through Expedia but the front desk person was helping me to resolve the issue."
The price is P7,472
P8,551 total
includes taxes & fees
Dec 1 - Dec 2
Fairfield Inn & Suites Wentzville
TownePlace Suites by Marriott Wentzville
In-room safe, desk, laptop workspace, blackout drapes

TownePlace Suites by Marriott Wentzville

3.0 star property
9.6 out of 10, Exceptional, (16)
"Very relaxing, clean, inviting, quiet and the staff were awesome!! Thank you!"
The price is P7,973
P9,681 total
includes taxes & fees
Dec 1 - Dec 2
TownePlace Suites by Marriott Wentzville
Holiday Inn Express Warrenton, an IHG Hotel
Lobby

Holiday Inn Express Warrenton, an IHG Hotel

2.5 star property
9.2 out of 10, Wonderful, (471)
"Great location, friendly staff, quiet room, clean and comfortable bed. Hot, delicious breakfast."
The price is P6,551
P7,500 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Express Warrenton, an IHG Hotel
Super 8 by Wyndham Washington
In-room safe, desk, blackout drapes, iron/ironing board

Super 8 by Wyndham Washington

2.0 star property
8.4 out of 10, Very Good, (598)
"Weird key issue- they stopped working when we went to breakfast. We didn’t check out yet but the card keys stopped working. Our friends had the same issue. "
The price is P4,205
P4,787 total
includes taxes & fees
Dec 8 - Dec 9
Super 8 by Wyndham Washington
The Inn at Elijah McLeans
Balcony view

The Inn at Elijah McLeans

4.0 star property
9.2 out of 10, Wonderful, (99)
"Very clean and customer service was great. We needed an early check in and they made it happen for us!"
The price is P8,408
P9,572 total
includes taxes & fees
Nov 27 - Nov 28
The Inn at Elijah McLeans
Central Hotel
Front of property

Central Hotel

3.5 star property
9.8 out of 10, Exceptional, (102)
"We really enjoyed our stay. "
The price is P9,130
P9,973 total
includes taxes & fees
Dec 5 - Dec 6
Central Hotel
Pinckney Bend Bed & Breakfast
Property grounds

Pinckney Bend Bed & Breakfast

3.0 star property
9.6 out of 10, Exceptional, (98)
"Delicious breakfast artfully arranged; hosts were very friendly and hospitable. Our little cabin was delightful and we enjoyed the view of the river very much. We would love to return!"
The price is P8,566
P9,357 total
includes taxes & fees
Dec 24 - Dec 25
Pinckney Bend Bed & Breakfast
Zia New Haven
Exterior

Zia New Haven

3.5 star property
9.6 out of 10, Exceptional, (5)
"We absolutely loved our stay. Laura was great!"
Zia New Haven
Extended Stay Warrenton Inn
Lobby

Extended Stay Warrenton Inn

2.0 star property
10.0 out of 10, Exceptional, (1)
"Love all of it "
The price is P3,868
P4,428 total
includes taxes & fees
Nov 27 - Nov 28
Extended Stay Warrenton Inn
Wine Country Getaway
Exterior

Wine Country Getaway

4.0 star property
The price is P7,726
P25,990 total
includes taxes & fees
Dec 2 - Dec 3
Wine Country Getaway
New Melle Apartment Near Missouri Wine Country
Private kitchen

New Melle Apartment Near Missouri Wine Country

3.0 star property
New Melle Apartment Near Missouri Wine Country
Historic Marthasville Getaway w/ Shared Amenities!
Private kitchen

Historic Marthasville Getaway w/ Shared Amenities!

3.0 star property
Historic Marthasville Getaway w/ Shared Amenities!
Historic Marthasville Home w/ Shared Amenities!
Outdoor spa tub

Historic Marthasville Home w/ Shared Amenities!

3.0 star property
Historic Marthasville Home w/ Shared Amenities!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Defiance
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are La Quinta Inn & Suites by Wyndham St. Louis Westport and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham. See all available top hotels, or vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

La Quinta Inn & Suites by Wyndham St. Louis Westport: Offers free self parking, an outdoor pool, and complimentary wireless internet access. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station and Enterprise Center. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Broemmelsiek Park, and Missouri River. A couple of additional sights to add to your agenda are Chandler Hill Vineyards and Sugar Creek Winery. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.