Sikeston Trips (flight + hotel)

Photo by Ryan Coleman

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to P 3,118 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P4,993 per night from Aug 10 to Aug 11
P4,993
P5,690 total
Aug 10 - Aug 11
includes taxes & fees
8.2/10 Very Good! (1,009 reviews)
"We were travelling through and were pleasantly surprised at how well maintained the hotel was. Also breakfast was great with eggs and biscuits and gravy. Would definitely stay again."

Reviewed on Jul 8, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P5,779 per night from Jul 20 to Jul 21
P5,779
P6,644 total
Jul 20 - Jul 21
includes taxes & fees
9.4/10 Exceptional! (1,006 reviews)
"The staff here from check in to the morning breakfast were welcoming and friendly. Cost was reasonable. I loved seeing the dogs and that it is pet friendly. Everything was clean. The location was close to places to eat - we even walked to El Bracero for dinner. I would highly recommend"

Reviewed on Jul 11, 2025

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P5,354 per night from Jul 19 to Jul 20
P5,354
P6,155 total
Jul 19 - Jul 20
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
"Excellent place to stay. Good breakfast choices. Good pool and hot tub."

Reviewed on Jul 9, 2025

Pear Tree Inn Sikeston
See all 260 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sikeston vacation package cost?
You'll find cheap prices on Expedia for your Sikeston getaway. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Sikeston costs.
What are the cheapest months to go to Sikeston?
January, February and September are the best times to look for cheap Sikeston vacation packages. Opting to travel in quieter periods means you'll typically find better prices on hotels and flights.
How many days is enough for Sikeston?
You can easily see all the top attractions in Sikeston in a few days, including the popular Sikeston Depot Museum. If you want an extended Sikeston vacation, check out which kind of excursions and activities are available nearby.
Is it worth booking a vacation package to Sikeston?
Sikeston has everything you need for an unforgettable trip. Begin your Sikeston vacation on a high note by exploring top attractions like Central Park.
How to find the best Sikeston package deals?
Use Expedia's filters to find some great Sikeston package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Sikeston package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Sikeston vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking stays and flights separately. Better still, you can tailor your Sikeston escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sikeston?
Enjoy incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Sikeston trip.
How to plan a trip to Sikeston?

  1. Choose the right time to travel: Your schedule, favorite season and the type of weather you like can all impact your decision on when to visit Sikeston.
  2. Set your budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Sikeston. Then, pick a hotel that suits your budget, whether that's an economical stay or a lavish retreat.
  3. Determine how many days away: Start by compiling a list of the attractions and activities you want to experience in Sikeston. Then, estimate how long you'll need at each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, hotels, car rental and more into a personalized Sikeston vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.