Photo by Cindy Keese

Seneca Hotels

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Seneca hotel prices

Tonight
Oct 1 - Oct 2
Tomorrow night
Oct 2 - Oct 3
This weekend
Oct 4 - Oct 6
Next weekend
Oct 11 - Oct 13

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Seneca hotels

Pet-friendly Central Cottage: 2 Miles to Clemson!
Exterior
Pet-friendly Central Cottage: 2 Miles to Clemson!
3.0 star property
Pet-friendly Central Cottage: 2 Miles to Clemson!
Best Western Plus Clemson Hotel & Conference Center
Down comforters, in-room safe, desk, laptop workspace
Best Western Plus Clemson Hotel & Conference Center
2.5 star property
8.2 out of 10, Very Good, (894)
"The staff were friendly and professional. The room was clean and the staff were attentive to my needs. "
The price is P5,431
P6,028 total
includes taxes & fees
Oct 8 - Oct 9
Best Western Plus Clemson Hotel & Conference Center
Days Inn by Wyndham Anderson
Premium bedding, pillowtop beds, in-room safe, desk
Days Inn by Wyndham Anderson
2.0 star property
7.2 out of 10, Good, (842)
"The room smelled and the bathroom light is a fire hazard. It comes on when it wants and flickers and you can't just push the button to turn it on because it is broken."
The price is P3,098
P3,439 total
includes taxes & fees
Oct 7 - Oct 8
Days Inn by Wyndham Anderson
Inn @ Clemson
Lobby lounge
Inn @ Clemson
2.5 star property
8.2 out of 10, Very Good, (1008)
"Staff was wonderful and very convenient to campus"
The price is P6,108
P6,780 total
includes taxes & fees
Oct 6 - Oct 7
Inn @ Clemson
Comfort Inn & Suites Clemson - University Area
Lobby
Comfort Inn & Suites Clemson - University Area
2.5 star property
8.2 out of 10, Very Good, (1001)
"The staff was amazing! They had a meet and greet snack station set up for those visiting Friday. They assisted with finding rides to the stadium too! It was wonderful! "
The price is P4,889
P5,427 total
includes taxes & fees
Oct 16 - Oct 17
Comfort Inn & Suites Clemson - University Area
Lakeside Lodge Clemson
Aerial view
Lakeside Lodge Clemson
2.5 star property
9.0 out of 10, Wonderful, (716)
"I wish I was staying longer. The hotel has many amenities I did not get to take advantage of. Great price since Clemson didn’t have a game. "
The price is P6,108
P7,531 total
includes taxes & fees
Oct 11 - Oct 12
Lakeside Lodge Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
8.2 out of 10, Very Good, (1005)
"Overall quite convenient. Very nice staff. "
The price is P4,051
P4,497 total
includes taxes & fees
Oct 17 - Oct 18
Microtel Inn & Suites by Wyndham Anderson/Clemson
Holiday Inn Express & Suites Clemson, an IHG Hotel
Exterior
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (817)
"Good as usual"
The price is P6,205
P6,888 total
includes taxes & fees
Oct 7 - Oct 8
Holiday Inn Express & Suites Clemson, an IHG Hotel
The Shepherd Hotel Downtown Clemson
In-room safe, blackout drapes, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (389)
"Thanks for a lovely stay!"
The price is P10,037
P11,141 total
includes taxes & fees
Oct 6 - Oct 7
The Shepherd Hotel Downtown Clemson
Quality Inn Clemson near University
Reception
Quality Inn Clemson near University
2.5 star property
7.0 out of 10, Good, (778)
"Everything was great"
The price is P2,786
P3,093 total
includes taxes & fees
Oct 16 - Oct 17
Quality Inn Clemson near University
Days Inn by Wyndham Seneca / Clemson Area
Lobby
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
6.8 out of 10, (638)
"I didn't like that there was 2 lines going up and down on my TV sceen"
The price is P4,001
P4,401 total
includes taxes & fees
Oct 8 - Oct 9
Days Inn by Wyndham Seneca / Clemson Area
Horizon Inn & Suites
Iron/ironing board, free WiFi, bed sheets, alarm clocks
Horizon Inn & Suites
2.0 star property
5.8 out of 10, (90)
"Close to everything.tv didnt work.they fix it the next day"
The price is P2,960
P3,453 total
includes taxes & fees
Oct 2 - Oct 3
Horizon Inn & Suites
Hilton Garden Inn Anderson
Exterior
Hilton Garden Inn Anderson
3.0 star property
8.8 out of 10, Excellent, (548)
"Easy to find. Very quiet. Friendly staff very comfy beds"
The price is P6,148
P6,824 total
includes taxes & fees
Oct 7 - Oct 8
Hilton Garden Inn Anderson
Comfort Suites Anderson-Clemson
Lobby
Comfort Suites Anderson-Clemson
2.5 star property
8.4 out of 10, Very Good, (925)
"Easy access to Clemson and Anderson. Nice hotel and comfortable accommodations."
The price is P5,335
P5,922 total
includes taxes & fees
Oct 17 - Oct 18
Comfort Suites Anderson-Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
9.4 out of 10, Exceptional, (116)
"This is a wonderful clean hotel. Great for game day or visit to Clemson University. My favorite in the area!"
The price is P7,233
P7,957 total
includes taxes & fees
Oct 6 - Oct 7
Fairfield Inn & Suites Seneca Clemson Univ Area
Quality Inn Seneca US-123
Pillowtop beds, desk, laptop workspace, blackout drapes
Quality Inn Seneca US-123
2.5 star property
7.8 out of 10, Good, (535)
"Great room at a great price"
The price is P3,992
P4,932 total
includes taxes & fees
Oct 27 - Oct 28
Quality Inn Seneca US-123
Tru by Hilton Seneca Clemson
Terrace/patio
Tru by Hilton Seneca Clemson
2.5 star property
9.2 out of 10, Wonderful, (624)
"N/A"
The price is P6,257
P6,883 total
includes taxes & fees
Oct 13 - Oct 14
Tru by Hilton Seneca Clemson
The Abernathy of Clemson
Flat-screen TV
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (447)
"Great hotel. Very convenient to the University. Clean, comfortable rooms. Friendly staff."
The price is P8,910
P9,890 total
includes taxes & fees
Oct 14 - Oct 15
The Abernathy of Clemson
Days Inn by Wyndham Clemson
Gazebo
Days Inn by Wyndham Clemson
3.5 star property
7.4 out of 10, Good, (118)
"Kishan the operations manager was fantastic "
The price is P4,474
P4,967 total
includes taxes & fees
Oct 6 - Oct 7
Days Inn by Wyndham Clemson
Baymont by Wyndham Anderson Clemson
Outdoor pool
Baymont by Wyndham Anderson Clemson
2.5 star property
7.0 out of 10, Good, (757)
"Needed a night away from my 3 year old to be in a dark cold room alone watching what I wanted on tv and sleeping in a big bed alone with all the room I could want or need and that’s what I got "
The price is P3,382
P3,754 total
includes taxes & fees
Oct 31 - Nov 1
Baymont by Wyndham Anderson Clemson
Don't see what you're looking for?
See all available properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best budget-friendly accommodation in Seneca?

Based on reviews, Quality Inn Seneca US-123 is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free breakfast and free WiFi. View all budget hotels in Seneca.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn & Suites Seneca-Clemson Area is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Hampton Inn & Suites Seneca-Clemson Area is a top hotel with a seasonal outdoor pool, free buffet breakfast, and free WiFi. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 266 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Natural beauty is on display at Lake Keowee, Lake Hartwell, and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. The university setting is a highlight and Clemson University is worth a campus tour. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.