Located in one of the most beautiful and oldest neighborhoods of Mexico City, the Blue House was converted into a museum in 1958, four years after the death of the painter. Today it is one of the busiest museums in the Mexican capital.

Coyoacán represents the "place of those who have or own coyotes", from three Nahua voices: coyotl (coyote), hua (possession) and can (place). The term coyoacanense, arose between the seventh and twelfth centuries AD, stage in which the site would have been founded, according to the parameters set by various historians and chroniclers

Throughout his life, Diego Rivera gathered an impressive collection of pre-Hispanic figures, which he called "idolaje". The painter conceived the idea of making a construction that would house these pieces and was, likewise, a livable artistic work.

On September 22, 1910, as President Porfirio Díaz Mori, the National University of Mexico was inaugurated, in compliance with the decree of May 16 of that year that formalized its Constitutive Law presented by Justo Sierra Méndez, 18 a law that did not give him the autonomous character that would acquire until May 28, 1929 when President Emilio Portes Gil granted it19 and authorized the construction of University City. The first rector was Joaquín Eguía Lis. The project of creation of the University, although without an immediate result, was proposed by Justo Sierra in 1881, being deputy and with the intention of counteracting the educational problem. The purpose of Sierra was materialized in 1910 with the inaugural act of the National University of Mexico, in the amphitheater of the National Preparatory School. At this time, being Secretary of Public Instruction and Fine Arts, Sierra, expressed in his speech, that the educational and scientific objective that the National University should concentrate, systematize and disseminate among the Mexican people, was to prepare for the future.