Midtown

St. Louis

Midtown
Photo by throwingsofas
Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit

Things to do


Top hotels in Midtown

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
The price is P6,704 per night from 27 Apr to 28 Apr
P6,704
P7,973 total
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,002 reviews)
"The customer service at check in was excellent"

Reviewed on Apr 5, 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
The price is P7,954 per night from 27 Apr to 28 Apr
P7,954
P9,301 total
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (475 reviews)
"We loved that the property has valet, kids loved the indoor pool since the weather wasnt perfect. Staff was AMAZING, we were on a road trip from south Mississippi and this was the second hotel we stayed in and it was 10 times better than the first. Breakfast was also AMAZING my husband who is usually ..."

Reviewed on Apr 4, 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
The price is P6,031 per night from 18 Apr to 19 Apr
P6,031
P7,113 total
includes taxes & fees
Apr 18 - Apr 19
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,606 reviews)
"I loved the property.The staff was very friendly and helpful. My only complaint is seeing bunches of sheets and towels in the hallway upon check-in. It was like 3:15pm. I was on the 10th floor, Rm 1005. Also, there was the same pieces of trash outside the same doors no matter when we went to our ..."

Reviewed on Apr 4, 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is P6,892 per night from 13 Apr to 14 Apr
P6,892
P8,059 total
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,458 reviews)
"Great breakfast and dinner options plus free drinks"

Reviewed on Apr 6, 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is P5,398 per night from 13 Apr to 14 Apr
P5,398
P6,288 total
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,001 reviews)
"It was a good place to stay and the breakfast was great!"

Reviewed on Apr 2, 2025

Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
4 out of 5
9801 Natural Bridge Road, St. Louis, MO
The price is P6,704 per night from 26 Apr to 27 Apr
P6,704
P7,843 total
includes taxes & fees
Apr 26 - Apr 27
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.2/10 Very Good! (1,010 reviews)
"Very nice hotel! Convenient location and price!"

Reviewed on Apr 7, 2025

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Midtown

Default Image

The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

Lafayette Square
Default Image

Shaw

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by Cathedral Basilica of St. Louis or World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove

Midtown