Santa María Trips (flight + hotel)

    deals illustration

    Better together

    Save up to P 3,118 when you book a flight and hotel together*
    stays illustration

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    luggage illustration

    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santa María

Hilton Cartagena
Hilton Cartagena
4.5 out of 5
Avenida Almirante Brion, El Laguito, Cartagena
Fully refundableReserve now, pay when you stay
The price is P8,423 per night from Aug 9 to Aug 10
P8,423
P8,423 total
Aug 9 - Aug 10
9/10 Wonderful! (1,077 reviews)
"The service at the restaurant was great. Waiters were very attentive."

Reviewed on Jul 4, 2025

Hilton Cartagena
Hyatt Regency Cartagena
Hyatt Regency Cartagena
4.5 out of 5
Carrera 1 No 12-118, Cartagena, CO
Fully refundableReserve now, pay when you stay
The price is P9,937 per night from Jul 15 to Jul 16
P9,937
P9,937 total
Jul 15 - Jul 16
9.2/10 Wonderful! (1,323 reviews)
"Great customer service, front desk personnel on top of everything. Housekeeping perfect. 10/10"

Reviewed on Jul 4, 2025

Hyatt Regency Cartagena
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
4 out of 5
Anillo Vial, Km 12, between Manzanillo, del Mar and Punta Canoa, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
The price is P16,246 per night from Aug 11 to Aug 12
P16,246
P16,246 total
Aug 11 - Aug 12
8.2/10 Very Good! (855 reviews)
"Our first family vacation after having our first baby was a success here at Dreams in Cartagena. The service was the best part of it all. All staff was very friendly. The premier lounge and spa teams were the most helpful for us. The premier lounge team was always there to assist with our needs. ..."

Reviewed on Jun 30, 2025

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
See all 3,657 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Blanca Beach

Blanca Beach

If a restful vacation is part of your travel plans, Blanca Beach might be the perfect place to seek out during your trip to Cartagena.

Blanca Beach
Isla Grande Beach

Isla Grande Beach

Why not spend a carefree afternoon at Isla Grande Beach during your travels in Rosario Islands? You can seek out the snorkeling spots in this relaxing area.

Isla Grande Beach
Las Bovedas

Las Bovedas

You can find the perfect gifts to bring home at Las Bovedas during your visit to Cartagena. Stroll along the area's beautiful beaches, or simply savor its top-notch restaurants.

Las Bovedas

What to do in Santa María

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

P3,383
per adult
80% of travellers recommend
The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat
Bora Bora Cartagena Beach Club Full Day Experience

Bora Bora Cartagena Beach Club Full Day Experience

P6,095
per adult
88% of travellers recommend
Bora Bora Cartagena Beach Club Full Day Experience
Sunset Cruise in Cartagena

Sunset Cruise in Cartagena

P1,579
per adult
88% of travellers recommend
Sunset Cruise in Cartagena
See all activities in Santa María

Frequently asked questions

How much does a Santa María vacation package cost?
You can grab a vacation package to this top destination on Expedia. However, how much your vacation to Santa María costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to Santa María?
April, September and October are the best times to search for cheap Santa María vacation packages. Traveling in less busy periods means you can generally find better prices on accommodations and flights.
How many days is enough for Santa María?
Usually, a handful of days is enough to see the main attractions during your Santa María vacation. However, if you'd like to have some time to relax or take day trips, think about extending your trip.
How to find the best Santa María package deals?
Landing a cheap Santa María package deal is a breeze with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most affordable Santa María package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Santa María vacation as a package?
You can enjoy significant savings on your next Santa Marían escape by booking a customized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Santa María?
If you've got your Santa María vacation dates finalized, book early to grab some fantastic deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for traveling on a whim.
How to plan a trip to Santa María?

  1. Pick your dates: The things you plan to do in Santa Marían and your preferred season will help you decide when to get away.
  2. Set your budget: Factor in expenses like flights, meals and transportation when working out how much to set aside for your trip to Santa María. Then, select a property that suits your budget, whether that's an economical stay or a high-end getaway.
  3. Decide your trip length: Think about how much time you'd like to spend discovering Santa María. Plan your itinerary so you can get to all the activities and attractions you're interested in without rushing.
  4. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left is to pick a Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.