Santa Clara Trips (flight + hotel)

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Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara
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Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Palacio de las Garzas while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Santa Clara

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is P6,688 per night from 28 Feb to 1 Mar
P6,688
P7,357 total
includes taxes & fees
Feb 28 - Mar 1
9/10 Wonderful! (3,652 reviews)
Very good!!
"Second time staying at this hotel. Breakfast buffet amazing. 20 min walking from the Cinta Costera."

Reviewed on Feb 19, 2025

Hotel Riu Plaza Panama
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is P5,813 per night from 6 Mar to 7 Mar
P5,813
P6,394 total
includes taxes & fees
Mar 6 - Mar 7
9.2/10 Wonderful! (1,874 reviews)
"Manager was accommodating upon check in as our room was not available until the next day so she upgraded our room for the entire stay."

Reviewed on Feb 19, 2025

Plaza Paitilla Inn Hotel
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is P22,195 per night from 17 Mar to 18 Mar
P22,195
P22,195 total
includes taxes & fees
Mar 17 - Mar 18
7.2/10 Good! (1,002 reviews)
"I loved the hotel and the staff were very friendly and helpful."

Reviewed on Feb 19, 2025

Dreams Playa Bonita Panama - All Inclusive
See all 1,391 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Clara vacation package cost?
Custom make your Santa Clara vacation package from as little as . Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we’ve got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That’s why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travelers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara vacation?
Savvy travelers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some vacation time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you’re looking for. If you’re traveling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you’ll pick up awesome discounts. Whether you’re organizing a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia vacation package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara vacation package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you’ve made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina

Things to do

Aerial view of the Panama Canal

Panama Canal Partial Transit

P8,748
per adult
84% of travellers recommend
Panama Canal Partial Transit
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

P8,693
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

P6,242
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.