Santa Clara Hotels

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Clara hotels

Villa Botero By Casa Mojito B&B

3.0 star property
9.8 out of 10, Exceptional, (60)
"Host was excellent. Great communication and very helpful. The rooms were nice and great value. "
Villa Botero By Casa Mojito B&B

The Golden Frog Inn

3.0 star property
9.8 out of 10, Exceptional, (198)
"It is like a tropical paradise. Beautiful, well landscaped grounds, friendly staff, quiet room apart from other rooms. We definitely want to come back."
The price is P4,950
P5,445 total
includes taxes & fees
Jul 7 - Jul 8
The Golden Frog Inn

Caracoral Hotel Boutique & Spa

3.0 star property
9.6 out of 10, Exceptional, (58)
"Beautiful hotel and wonderful staff. We really enjoyed our stay."
Caracoral Hotel Boutique & Spa

Gran Evenia Bijao & Convention Center

3.5 star property
7.8 out of 10, Good, (883)
"Amazing beach and good meals "
The price is P8,051
P8,856 total
includes taxes & fees
Jul 8 - Jul 9
Gran Evenia Bijao & Convention Center

Refugio Cariguana

2.5 star property
4.0 out of 10, (2)
The price is P4,734
P5,207 total
includes taxes & fees
Jul 5 - Jul 6
Refugio Cariguana

Hotel Campestre

3.0 star property
8.2 out of 10, Very Good, (232)
"The Manager, Rick, was engaging, flexible and friendly "
The price is P5,126
P5,638 total
includes taxes & fees
Jul 7 - Jul 8
Hotel Campestre

Hotel Coronado Inn

3.0 star property
8.2 out of 10, Very Good, (69)
"Restaurant had good food, pool was nice room was very clean, building very clean, building was surrounded by everything you need. Grocery stores Restaurants, banks all surrounded this Hotel. Staff was very friendly!"
Hotel Coronado Inn

Playa Blanca Beach Resort - All Inclusive

4.0 star property
6.8 out of 10, (1008)
"Location was nice but is lacking cleaning around pool and eating areas. Perhaps restricting any drinking inside the pool. "
The price is P7,884
P8,672 total
includes taxes & fees
Jul 10 - Jul 11
Playa Blanca Beach Resort - All Inclusive

El litoral

3.0 star property
9.6 out of 10, Exceptional, (57)
"It was a beautiful and relaxing place. Very clean and comfortable. "
The price is P7,116
P7,828 total
includes taxes & fees
Jul 10 - Jul 11
El litoral

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5.0 star property
9.2 out of 10, Wonderful, (642)
"Staff was polite and attentive but not overbearing. Well maintained property and excellent food."
The price is P10,351
P11,386 total
includes taxes & fees
Jul 10 - Jul 11
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

Hotel Las Catalinas Antón

2.5 star property
8.4 out of 10, Very Good, (25)
"The hotel is very unique and quaint, very warm and comfortable. The location is so charming in the old town. There was a little parade and the church bells ring with the Sunday morning. A great staff so helpful and kind. We can not wait to return. "
The price is P2,405
P2,646 total
includes taxes & fees
Jul 6 - Jul 7
Hotel Las Catalinas Antón

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 star property
7.4 out of 10, Good, (1010)
"Peaceful, really nice staff and the food is good. "
The price is P8,224
P9,047 total
includes taxes & fees
Jul 14 - Jul 15
Grand Decameron Panama, A Trademark All Inclusive Resort

Manglar Lodge

3.0 star property
8.8 out of 10, Excellent, (202)
"Nice place I’d go back"
The price is P4,500
P4,950 total
includes taxes & fees
Jul 5 - Jul 6
Manglar Lodge

Apartamento en Playa Blanca Town Center

3.0 star property
7.6 out of 10, Good, (44)
"Very nice unit in the playa Blanca town centre. "
Apartamento en Playa Blanca Town Center

Cabaña Villa Victoria

2.5 star property
9.6 out of 10, Exceptional, (45)
"The property is beautiful and Victoria is kind and gracious ."
Cabaña Villa Victoria

Acuarela Hostal - Hostel

2.0 star property
8.6 out of 10, Excellent, (23)
"Was a lovely lovely stay. The breakfast was excellent, and the family staff was so kind and accommodating. "
The price is P2,250
P2,475 total
includes taxes & fees
Jul 5 - Jul 6
Acuarela Hostal - Hostel

Hostal Corotu

2.0 star property
5.6 out of 10, (4)
"Don Nando muy buena persona pero creo q pague mucho porq hay sitios mejores como el hostal del señor Miguel moly q es muy bonito y con picina y el restaurante es exquisita la comida En el coro tú no hay personal q te atienda "
The price is P2,869
P3,156 total
includes taxes & fees
Jul 5 - Jul 6
Hostal Corotu

Town Center Paradise in Playa Blanca

2.5 star property
8.0 out of 10, Very Good, (42)
"Nice"
Town Center Paradise in Playa Blanca

La Maracuyá

4.0 star property
9.8 out of 10, Exceptional, (8)
"Nice place and nice ladies who run the place. Thoughtful touches "
La Maracuyá

Hotel La Compania Del Valle

5.0 star property
9.6 out of 10, Exceptional, (19)
"Great place to stay and relax Beautiful "
The price is P14,058
P15,464 total
includes taxes & fees
Jul 8 - Jul 9
Hotel La Compania Del Valle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

These resorts in Santa Clara may fit your trip

Check out cabins in Santa Clara

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Clara

Like beaches? Get away to romantic Santa Clara!

Frequently asked questions

Where is the best place to stay in Santa Clara?

Villa Botero By Casa Mojito B&B is one of the top choices for your stay based on our traveler data. This B&B offers an outdoor pool and free parking. Las Sirenas de Santa Clara is another good option for your visit. See all available top hotels, or vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

For more details about updating your trip to Santa Clara or cancelling it, click here.

What's the best accommodation when traveling with kids to Santa Clara?

Las Sirenas de Santa Clara is a top 3-star villa on Expedia for families, and features in-room kitchens and free parking. Attractions in the area like Serpentarium are also fun for the whole family.

What is the top LGBTQ-friendly place to stay in Santa Clara?

Villa Botero By Casa Mojito B&B is a top LGBTQ-friendly B&B that features free WiFi and free parking. See all available hotels listed as LGBTQ-friendly in Santa Clara.

What's the best pet-friendly hotel in Santa Clara?

Villa Botero By Casa Mojito B&B is a top B&B for people traveling with their pets, and offers an outdoor pool and a bar/lounge for its human guests. See more pet-friendly hotel accommodations in Santa Clara.

What's the best hotel to stay near the beach in Santa Clara?

Villa Botero By Casa Mojito B&B is a top beach B&B offering free WiFi and free parking, located within a short 13-minute walk of Santa Clara Beach. See more stays near the beach in Santa Clara.

What are some hotels with pools in Santa Clara?

Villa Botero By Casa Mojito B&B: B&B located near Playa Blanca. Features spa services, an outdoor pool, and a snack bar/deli. Gran Evenia Bijao & Convention Center and Grand Decameron Panama, A Trademark All Inclusive Resort are two additional hotels with an onsite pool. View all hotels with pools in Santa Clara.

What is the best spa hotel in Santa Clara?

Villa Botero By Casa Mojito B&B is a top spa hotel featuring a bar and an outdoor pool. In-room massages are also available. See all spa hotels in Santa Clara.

What is the best accommodation for staying close to Tocumen International Airport (PTY)?

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer including its beaches. Tourists to the city can also enjoy its scenic landscape. A top sight in the area is Playa Blanca. In Santa Clara, there are 14 hotels and other accommodations to choose from. Find out more about Santa Clara.

What is there to see in Santa Clara?

A favorite place to visit is Santa Clara Beach. Additionally, you'll find Playa Blanca in the area. Check out what more to see and do in Expedia's Santa Clara guide.

What's the seasonal weather like in Santa Clara?

The hottest months are usually March and April with an average temp of 79°F, while the coldest months are January and December with an average of 78°F. The rainiest months in Santa Clara are October, November, September, and August, with each month seeing an average of 13 inches of rainfall.