Santa Ana

Antigua Guatemala

Popular places to visit

Casa Santo Domingo Museum

Casa Santo Domingo Museum

You can browse the exhibits at Casa Santo Domingo Museum, a museum with a story of its own, during your travels to Antigua Guatemala. Discover the volcano viewpoints and shops in this romantic area.

Casa Santo Domingo Museum
Central Park

Central Park

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Central Park
Antigua Guatemala Cathedral

Antigua Guatemala Cathedral

You can find out about the history of Antigua Guatemala with a visit to Antigua Guatemala Cathedral. Discover the area's shops, or seek out its local tours.

Antigua Guatemala Cathedral
Santa Catalina Arch

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this family-friendly area.

Santa Catalina Arch
La Merced Church

La Merced Church

Learn about the local history of Antigua Guatemala when you take a trip to La Merced Church. Discover the area's volcano viewpoints and shops.

La Merced Church
Las Capuchinas Convent

Las Capuchinas Convent

You can find out about the history of Antigua Guatemala with a visit to Las Capuchinas Convent. Discover the volcano viewpoints and shops in this romantic area.

Las Capuchinas Convent

Things to do

Lake Atitlan One Day Tour

Lake Atitlan One Day Tour from Antigua

P5,275
per adult
96% of travellers recommend
Lake Atitlan One Day Tour from Antigua
Tour in Hobbitenango on ATV or UTV

Tour in Hobbitenango on ATV or UTV

P4,302
per adult
100% of travellers recommend
Tour in Hobbitenango on ATV or UTV
From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

P1,319
per adult
86% of travellers recommend
From Antigua: Pacaya Volcano Trek
Overnight Adventure !!Hike Acatenango Volcano

Overnight Adventure !!Hike Acatenango Volcano

P4,588
per adult
Overnight Adventure !!Hike Acatenango Volcano
Antigua Sky High Adventure

Antigua Sky High Adventure

P3,728
per adult
100% of travellers recommend
Antigua Sky High Adventure
Guided Tour to Altamira by ATV or UTV

Guided Tour to Altamira by ATV or UTV

P4,302
per adult
Guided Tour to Altamira by ATV or UTV
See all activities in Antigua Guatemala

Top hotels in Santa Ana

Barceló Guatemala City
Barceló Guatemala City
4.5 out of 5
7 Avenida 15-45, Zona 9, Guatemala City, Guatemala
The price is P4,609 per night from 21 Apr to 22 Apr
P4,609
P5,623 total
includes taxes & fees
Apr 21 - Apr 22
Stay at this 4.5-star luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in ...
9/10 Wonderful! (2,809 reviews)
"Todo estuvo excelente"

Reviewed on Apr 14, 2025

Barceló Guatemala City
Wyndham Garden Guatemala City
Wyndham Garden Guatemala City
4 out of 5
1a Avenida 12-46 Zona 10, Guatemala City, Guatemala
The price is P4,260 per night from 19 Apr to 20 Apr
P4,260
P5,197 total
includes taxes & fees
Apr 19 - Apr 20
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,314 reviews)
"Excellent option in the heart of Guatemala city"

Reviewed on Apr 14, 2025

Wyndham Garden Guatemala City
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez
The price is P13,193 per night from 23 Apr to 24 Apr
P13,193
P16,789 total
includes taxes & fees
Apr 23 - Apr 24
Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,006 reviews)
"Excellent staff"

Reviewed on Apr 8, 2025

Hotel Museo Spa Casa Santo Domingo
Tikal Futura Hotel & Convention Center
Tikal Futura Hotel & Convention Center
4.5 out of 5
Calzada Roosevelt 22-43, Zona 11, Guatemala City, Guatemala
The price is P6,748 per night from 20 Apr to 21 Apr
P6,748
P8,233 total
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this spa hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,000 reviews)
"Always stay here for proximity to where I need to be. Rooms are spacious, clean"

Reviewed on Apr 14, 2025

Tikal Futura Hotel & Convention Center
Hotel Las Americas
Hotel Las Americas
4 out of 5
Avenida Las Americas 9-08, Zona 13, Guatemala City, Guatemala
The price is P6,201 per night from 17 Apr to 18 Apr
P6,201
P7,566 total
includes taxes & fees
Apr 17 - Apr 18
Stay at this 4-star business-friendly hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
8/10 Very Good! (932 reviews)
"Excellent stay wonderfull place and safe def. Will stay here again"

Reviewed on Apr 9, 2025

Hotel Las Americas
The Westin Camino Real, Guatemala
The Westin Camino Real, Guatemala
4.5 out of 5
Calle Camino Real 0-20, Zona 10, Guatemala City, Guatemala
The price is P5,891 per night from 25 Apr to 26 Apr
P5,891
P7,187 total
includes taxes & fees
Apr 25 - Apr 26
Stay at this 4.5-star luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (956 reviews)
"Service is great and rooms are beautful. The rooms on the 9th executive floor only have a single door between them so noise is easily heard through the door. Hot tub was very dirty the second day we were there but overall a very nice hotel."

Reviewed on Mar 30, 2025

The Westin Camino Real, Guatemala
See all 1,064 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

Only a small part of the GIANT outdoor grounds. This is a hotel you can reserve and stay at, even thought it is literally inside the old church ruins, with museums onsite. Very inexpensive for American dollars.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
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Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Antigua Guatemala Cathedral.

Historic Center

Santa Ana