San Francisco Trips (flight + hotel)

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Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
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Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Centennial Park and Malecon 2000 while you're in town.

Find hotels in Downtown Guayaquil

Top hotels in San Francisco

Wyndham Guayaquil Puerto Santa Ana
Wyndham Guayaquil Puerto Santa Ana
4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is P5,779 per night from 23 Feb to 24 Feb
P5,779
P6,501 total
includes taxes & fees
Feb 23 - Feb 24
9.2/10 Wonderful! (1,003 reviews)
"Did not receive VIP benefits"

Reviewed on Feb 14, 2025

Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil
Oro Verde Guayaquil
5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is P5,090 per night from 9 Mar to 10 Mar
P5,090
P5,744 total
includes taxes & fees
Mar 9 - Mar 10
9.4/10 Exceptional! (1,004 reviews)
"Very professional staff. They make you feel welcomed to their hotel. One of the best hotels in Guayaquil. The breakfast bar is outstanding."

Reviewed on Feb 12, 2025

Oro Verde Guayaquil
TRYP by Wyndham Guayaquil Airport
TRYP by Wyndham Guayaquil Airport
4.5 out of 5
Av. Joaquín Orrantia y L. Benitez, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is P5,206 per night from 23 Feb to 24 Feb
P5,206
P5,871 total
includes taxes & fees
Feb 23 - Feb 24
8.6/10 Excellent! (1,004 reviews)
"Un hotel hermosa, ahora es mi única en Guayaquil"

Reviewed on Feb 8, 2025

TRYP by Wyndham Guayaquil Airport
See all 351 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Francisco vacation package cost?
From as little as . Yes, you read that right. Our San Francisco vacation packages are a simple way to make your dollars go much further. Bundle your hotels, flights and car rentals and discover this popular destination.
How do I get a cheap travel package to San Francisco?
Browse and lock in everything all in one place with our San Francisco vacation packages. We have deals on hotels, flights, tours and more that’ll keep your wallet happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 properties globally to select from, you’ll have endless opportunities to mix and match as you please.
How far in advance should I book my San Francisco vacation?
Search Expedia to compare airfares as soon as you know your travel dates. In many cases, you can purchase a ticket up to a year before departure. If you don’t see your preferred carrier, or you have to book last minute, don’t worry. The lowest prices to San Francisco occasionally appear within weeks of departure.
What does an Expedia San Francisco travel package include?
That depends on what sort of getaway you’re contemplating. San Francisco travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that works for you! You can also add on experiences and activities after you’ve booked to get even bigger discounts.
What should I know before booking a San Francisco travel package?
So many places to travel to, so many things to see. With a package, you’ll be able to cross more of them off your list. Combine your hotels, rental cars and flights and see how much you save.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, you can. We have more than 550 partner airlines worldwide, so fly with the carrier that best suits your travel preferences.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Certainly, and we’re here to help. You may be able to cancel and rebook your San Francisco vacation package at no cost if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, browse our Customer Service Portal for more information.

Popular places to visit

Santa Ana Hill

Santa Ana Hill

Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.

Santa Ana Hill

Guayaquil Historic Park

Explore the great outdoors at Guayaquil Historic Park, a lovely green space in Samborondon. While you're in the area, find time to visit its shops.

Guayaquil Historic Park

Riocentro Entre Rios

During your trip to Samborondon, you can search for that perfect souvenir at Riocentro Entre Rios. Visit the area's cathedral, or simply enjoy its seafood restaurants.

Riocentro Entre Rios

Things to do

From Montañita: Paragliding Experience

From Montañita: Paragliding Experience

P3,209
per adult
From Montañita: Paragliding Experience
On our City tours to the city of Guayaquil we want our clients to live a unique and memorable experience. Our main value is personalized attention, which is complemented by the history and traditions

Half Day Guayaquil History Tour and Ecuadorian Cuisine with Cocoa

P5,834
per adult
Half Day Guayaquil History Tour and Ecuadorian Cuisine with Cocoa
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

P3,442
per adult
Wine Tasting Experience with Tasting Menu
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.