San Francisco Hotels

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Top 10 trending San Francisco hotels

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (516)
"Very nice hotel and rooms ."
The price is P4,858
P5,344 total
includes taxes & fees
Jun 27 - Jun 28
Hotel Mykonos Panama

Hotel Galería

3.0 star property
8.4 out of 10, Very Good, (185)
"SC"
The price is P3,657
P4,023 total
includes taxes & fees
Jun 29 - Jun 30
Hotel Galería

Hotel Gran David

3.5 star property
8.4 out of 10, Very Good, (309)
"Great place to stay for the night on the way to Boquete from Panama City. "
Hotel Gran David

HOTEL VISTA LAGO

3.0 star property
9.4 out of 10, Exceptional, (54)
"Really a good Hotel for the price"
The price is P4,372
P4,809 total
includes taxes & fees
Jun 27 - Jun 28
HOTEL VISTA LAGO

Hotel Anachoreo

3.0 star property
9.4 out of 10, Exceptional, (34)
"Phenomenal property, Cambodian meals, great property and excellent customer service. The views are breathtaking from almost every room and the on site garden is wonderful to walk in…..the owner is also the cook at night……WOW! Hope this area stays just like it is. "
Hotel Anachoreo

La Qhia Eco Retreat

2.5 star property
8.0 out of 10, Very Good, (18)
"Very noisy due to neighbouring roosters & dogs at night. Food good & easy access. "
La Qhia Eco Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about San Francisco

Check out Parque Acuatico Italia Guadalupe Panama and Parque Nacional Cerro Hoya—just a couple of the sights around San Francisco.

Frequently asked questions

What's the best place for a stay in San Francisco?

Hotel Mykonos Panama, located 10.4 mi (16.8 km) from the heart of San Francisco, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hotel Galería and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

To find more details about picking new dates or cancelling your trip to San Francisco, click here.

What is staying in San Francisco like?

Visitors to San Francisco are sure to find plenty to explore and enjoy. There are 16 hotels and other accommodations in the surrounding area. Find out more about San Francisco.

What should I see while I'm in San Francisco?

Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Parque Nacional Cerro Hoya, and Catedral of Santiago Apostol. You'll also find Laguna de La Yeguada and Los Pozos Termales in the area. Check out what more to see and do in Expedia's San Francisco guide.

What's the weather like in San Francisco?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in San Francisco are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.