Medical Center District

San Antonio

Photo by Linda Cronan
Photo by Linda Cronan

Popular places to visit

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

South Texas Medical Center

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

CHRISTUS Santa Rosa Hospital - Medical Center

Though CHRISTUS Santa Rosa Hospital - Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

CHRISTUS Santa Rosa Hospital - Medical Center

University Hospital - University Health System

Though University Hospital - University Health System might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University Hospital - University Health System

Methodist Healthcare

Though Methodist Healthcare might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

Methodist Healthcare

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

P1,997
per adult
90% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
Best of San Antonio Tour

Best of San Antonio Tour

P9,096
per adult
94% of travellers recommend
Best of San Antonio Tour
San Antonio: Witte Museum Admission Ticket

San Antonio: Witte Museum Admission Ticket

P943
per adult
100% of travellers recommend
San Antonio: Witte Museum Admission Ticket
San Antonio: San Antonio Zoo Any Day Ticket

San Antonio: San Antonio Zoo Any Day Ticket

P2,163
per adult
96% of travellers recommend
San Antonio: San Antonio Zoo Any Day Ticket
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall

San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall

P2,320
per adult
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
Hop on Board the Ghost Bus

The Haunted Ghost Bus Tour in San Antonio

P3,051
per adult
96% of travellers recommend
The Haunted Ghost Bus Tour in San Antonio
See all activities in San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is P4,939 per night from Jun 11 to Jun 12
P4,939
P5,838 total
Jun 11 - Jun 12
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,570 reviews)
"Staff was kind and the breakfast so good"

Reviewed on Jun 4, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is P5,311 per night from Jun 12 to Jun 13
P5,311
P6,311 total
Jun 12 - Jun 13
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,007 reviews)
"The elevator was broke except one the whole time. Just a little inconvenience. Rooms were great & staff super helpful & friendly. I would stay there again."

Reviewed on Jun 2, 2025

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
The price is P5,561 per night from Jun 17 to Jun 18
P5,561
P6,574 total
Jun 17 - Jun 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,256 reviews)
"The elevators need repaired. It's been over a year and still not fixed."

Reviewed on Jun 4, 2025

Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio
3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is P5,169 per night from Jun 14 to Jun 15
P5,169
P6,110 total
Jun 14 - Jun 15
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,000 reviews)
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Reviewed on May 26, 2025

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is P4,850 per night from Jul 6 to Jul 7
P4,850
P5,733 total
Jul 6 - Jul 7
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (5,302 reviews)
"Very nice and welcoming"

Reviewed on Jun 3, 2025

Riverwalk Plaza
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3 out of 5
303 Blum Street, San Antonio, TX
The price is P4,956 per night from Jun 8 to Jun 9
P4,956
P6,931 total
Jun 8 - Jun 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.6/10 Good! (3,542 reviews)
"The stay stayed out rocky with various issues in the room. When I brought it up with the front desk in the morning they acted swiftly to move me to a new room, and upgrade me. Stuff happens so really no complaints."

Reviewed on Jun 3, 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
See all 4,383 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

If you're looking for some top things to see and do in Northwest Los Angeles Heights and surrounding area, you can visit Woodlawn Theater and San Antonio Zoo and Aquarium.

Northwest Los Angeles Heights
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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
It's Texas, of course everything is bigger! #guinessworldrecord #visittexas #hdr #fisheye

Shearer Hills - Ridgeview

If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and Blessed Sacrament Catholic Church are top sights worth seeing.

Shearer Hills - Ridgeview
Brackenridge Park

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

If you're spending some time in Tobin Hill, San Antonio River and Temple Beth-El are top sights worth seeing.

Tobin Hill

Medical Center District