Medical Center District

San Antonio

Photo by Linda Cronan
Photo by Linda Cronan

Popular places to visit

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

South Texas Medical Center

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

University Hospital - University Health System

Though University Hospital - University Health System might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University Hospital - University Health System

CHRISTUS Santa Rosa Hospital - Medical Center

Though CHRISTUS Santa Rosa Hospital - Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

CHRISTUS Santa Rosa Hospital - Medical Center

Methodist Healthcare

Though Methodist Healthcare might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

Methodist Healthcare

Things to do

San Antonio CityPASS®

San Antonio CityPASS®: Save on admission to 4 must-see attractions

P3,496
per adult
San Antonio CityPASS®: Save on admission to 4 must-see attractions
San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

P2,030
per adult
90% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
Unknown Atmospheres by Seth Nehil and Parallel Studio

Hopscotch Immersive Art Experience

P1,353
per adult
98% of travellers recommend
Hopscotch Immersive Art Experience
SEA LIFE San Antonio

SEA LIFE San Antonio

P1,525
per adult
78% of travellers recommend
SEA LIFE San Antonio
Best of San Antonio Tour

Best of San Antonio Tour

P9,246
per adult
94% of travellers recommend
Best of San Antonio Tour
San Antonio: Witte Museum Admission Ticket

San Antonio: Witte Museum Admission Ticket

P958
per adult
100% of travellers recommend
San Antonio: Witte Museum Admission Ticket
See all activities in San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is P5,011 per night from Jul 7 to Jul 8
P5,011
P5,922 total
Jul 7 - Jul 8
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,688 reviews)
"Excellent"

Reviewed on Jul 5, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is P5,372 per night from Jul 10 to Jul 11
P5,372
P6,383 total
Jul 10 - Jul 11
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,000 reviews)
"Highly recommend for the price"

Reviewed on Jul 2, 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is P5,191 per night from Jul 13 to Jul 14
P5,191
P6,061 total
Jul 13 - Jul 14
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (898 reviews)
"Staff very friendly, property clean and the breakfast was unbelievable i have not ever been to a hotel were breakfast has such a huge selection awesome I will be returning"

Reviewed on Jun 29, 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio
3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is P5,530 per night from Jul 21 to Jul 22
P5,530
P6,537 total
Jul 21 - Jul 22
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,000 reviews)
"I like it was very close to medical center."

Reviewed on Jun 30, 2025

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is P4,920 per night from Jul 28 to Jul 29
P4,920
P5,816 total
Jul 28 - Jul 29
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (5,458 reviews)
"The hotel is Ok ,"

Reviewed on Jul 4, 2025

Riverwalk Plaza
La Cantera Resort & Spa
La Cantera Resort & Spa
4 out of 5
16641 La Cantera Pkwy, San Antonio, TX
The price is P12,995 per night from Jul 7 to Jul 8
P12,995
P18,516 total
Jul 7 - Jul 8
includes taxes & fees
Stay at this 4-star spa hotel in San Antonio. Enjoy 5 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,010 reviews)
"Everything was great"

Reviewed on Jul 4, 2025

La Cantera Resort & Spa
See all 4,497 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

If you're looking for some top things to see and do in Northwest Los Angeles Heights and surrounding area, you can visit San Antonio Zoo and Aquarium and San Antonio River.

Northwest Los Angeles Heights
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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Northwest Side
It's Texas, of course everything is bigger! #guinessworldrecord #visittexas #hdr #fisheye

Shearer Hills - Ridgeview

If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and Blessed Sacrament Catholic Church are top sights worth seeing.

Shearer Hills - Ridgeview
Brackenridge Park

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

If you're spending some time in Tobin Hill, San Antonio River and Temple Beth-El are top sights worth seeing.

Tobin Hill

Medical Center District