Medical Center District

San Antonio

Photo by Linda Cronan
Photo by Linda Cronan

Popular places to visit

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

South Texas Medical Center

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

CHRISTUS Santa Rosa Hospital - Medical Center

Though CHRISTUS Santa Rosa Hospital - Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

CHRISTUS Santa Rosa Hospital - Medical Center

University Hospital - University Health System

Though University Hospital - University Health System might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University Hospital - University Health System

Methodist Healthcare

Though Methodist Healthcare might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

Methodist Healthcare

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

P2,023
per adult
90% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
Best of San Antonio Tour

Best of San Antonio Tour

P9,214
per adult
94% of travellers recommend
Best of San Antonio Tour
San Antonio: Witte Museum Admission Ticket

San Antonio: Witte Museum Admission Ticket

P955
per adult
100% of travellers recommend
San Antonio: Witte Museum Admission Ticket
San Antonio: San Antonio Zoo Any Day Ticket

San Antonio: San Antonio Zoo Any Day Ticket

P2,191
per adult
96% of travellers recommend
San Antonio: San Antonio Zoo Any Day Ticket
SEA LIFE San Antonio

SEA LIFE San Antonio

P1,520
per adult
78% of travellers recommend
SEA LIFE San Antonio
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall

San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall

P2,349
per adult
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
See all activities in San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is P4,910 per night from Jun 29 to Jun 30
P4,910
P5,804 total
Jun 29 - Jun 30
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,659 reviews)
"Good"

Reviewed on Jun 25, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is P5,399 per night from Jul 10 to Jul 11
P5,399
P6,415 total
Jul 10 - Jul 11
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,010 reviews)
"Down sides for us. There was no microwave in our room and I was told there would be, and the ice is not on every floor. It’s kept on one floor. Other than that it is well kept/clean, bed was comfortable and my room stayed cool… I can’t sleep in a hot room so this was was a major plus! Over all it ..."

Reviewed on Jun 21, 2025

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio
3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is P5,557 per night from Jul 6 to Jul 7
P5,557
P6,569 total
Jul 6 - Jul 7
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,003 reviews)
"I really enjoyed the set up. It was spacious and the pool was in the middle of everything. It was peaceful and i enjoyed my stay. Highly recommend if you are in San Antonio near The Lady of the Lake Unversity."

Reviewed on Jun 19, 2025

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is P4,945 per night from Jul 6 to Jul 7
P4,945
P5,845 total
Jul 6 - Jul 7
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (5,403 reviews)
"Rooms are clean and great view but they are small and had details like a broken shower head ect."

Reviewed on Jun 25, 2025

Riverwalk Plaza
Sonesta ES Suites San Antonio Downtown Alamo Plaza
Sonesta ES Suites San Antonio Downtown Alamo Plaza
3 out of 5
425 Bonham, San Antonio, TX
The price is P5,543 per night from Jul 6 to Jul 7
P5,543
P6,553 total
Jul 6 - Jul 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,604 reviews)
"Great room space"

Reviewed on Jun 24, 2025

Sonesta ES Suites San Antonio Downtown Alamo Plaza
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3 out of 5
303 Blum Street, San Antonio, TX
The price is P4,491 per night from Jul 6 to Jul 7
P4,491
P6,392 total
Jul 6 - Jul 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.6/10 Good! (3,560 reviews)
"Perfect for something near riverwalk."

Reviewed on Jun 25, 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
See all 4,398 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
It's Texas, of course everything is bigger! #guinessworldrecord #visittexas #hdr #fisheye

Shearer Hills - Ridgeview

If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and Blessed Sacrament Catholic Church are top sights worth seeing.

Shearer Hills - Ridgeview
Brackenridge Park

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

If you're spending some time in Tobin Hill, San Antonio River and Temple Beth-El are top sights worth seeing.

Tobin Hill
Marion Koogler McNay Art Museum featuring art and interior views

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and San Antonio River.

Uptown

Medical Center District