Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.
Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.Opens in a new window
Enjoy maximum flexibility with penalty-free cancellation on most car rentals.
Find Routes Car Pickup Locations near Santa Mesa
Find Popular Airports close to Santa Mesa
Car Rentals Suppliers at Santa Mesa
- Alamo Rent A Car car rentals in Santa Mesa
- Budget car rentals in Santa Mesa
- Enterprise car rentals in Santa Mesa
- Hertz car rentals in Santa Mesa
- Thrifty Car Rental car rentals in Santa Mesa
- Avis car rentals in Santa Mesa
- Dollar Rent A Car car rentals in Santa Mesa
- Sixt car rentals in Santa Mesa
- National car rentals in Santa Mesa
- Fox Rental Cars car rentals in Santa Mesa
- Payless car rentals in Santa Mesa
- Europcar car rentals in Santa Mesa
Car Types in Santa Mesa
- Mini car rentals in Santa Mesa
- Economy car rentals in Santa Mesa
- Compact car rentals in Santa Mesa
- Midsize car rentals in Santa Mesa
- Standard car rentals in Santa Mesa
- Fullsize car rentals in Santa Mesa
- Premium car rentals in Santa Mesa
- Luxury car rentals in Santa Mesa
- Convertible car rentals in Santa Mesa
- Minivan car rentals in Santa Mesa
- Van car rentals in Santa Mesa
- SUV car rentals in Santa Mesa
- Pickup car rentals in Santa Mesa
- Sportscar car rentals in Santa Mesa
Neighborhoods with Routes
Airports with Routes
Flying to Santa Mesa? Explore Santa Mesa with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more!
Expedia's Latest Trends
Hotels
Budget Hotels in MalateHotels in SampalocHotels with Hot Tubs in CubaoBudget Hotels in AlabangHotels in AlabangHotels with Swimming Pool in AlabangBudget Hotels in Ortigas CenterHotels with Swimming Pool in CubaoHotels in CubaoHotels with Early Check In in Makati DowntownBudget Hotels in CubaoHotels in Bonifacio Global CityBudget Hotels in IntramurosHotels with Hot Tubs in AlabangHotels in ErmitaBudget Hotels in Ermita