Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing animals, zoo animals and flowers
South Beach featuring a coastal town and a beach as well as a large group of people
South Beach featuring a luxury hotel or resort, swimming and a sandy beach
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point

Southernmost Point

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing zoo animals, animals and food

Key West Butterfly and Nature Conservatory

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

P892
per traveler
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

P875
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

P1,750
per adult
Bahama Village Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

P2,333
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

P525
per traveler
Florida Key West Self-Guided Walking Audio Tour Via App
Climb the 88 stairs to the top of the Key West Lighthouse.

Maritime Village to Micro State: A Self Guided Tour of Key West

P699
per adult
Maritime Village to Micro State: A Self Guided Tour of Key West
See all activities in Key West

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is P26,420 per night from 26 Feb to 27 Feb
P26,420
P33,627 total
includes taxes & fees
Feb 26 - Feb 27
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,276 reviews)
"Many activities at this location. Close to restaurants no need for a car"

Reviewed on Feb 15, 2025

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is P30,546 per night from 24 Feb to 25 Feb
P30,546
P38,008 total
includes taxes & fees
Feb 24 - Feb 25
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (869 reviews)
"Great staff and service, we really enjoyed our stay here! Lillie at the pool was amazing, great food and drinks. Prices were pretty high on everything, some repairs to the facility needed, only one working elevator on site. Overall a very good experience and we will be back!"

Reviewed on Feb 15, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is P23,371 per night from 23 Feb to 24 Feb
P23,371
P28,895 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,016 reviews)
"We had a very nice stay. Having a beach right there was excellent. The Southernmost Cafe had great food. The parking and resort fees were high."

Reviewed on Feb 15, 2025

The Southernmost Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is P16,776 per night from 23 Feb to 24 Feb
P16,776
P20,500 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,066 reviews)
"We have stayed here several times in the past 10 years. The front desk representative here now is so nice and so helpful, made us feel very welcome. It is modest but clean and convenient with three pools - we like to stay in the little courtyard with the smallest pool - nice and deep and warm and ..."

Reviewed on Feb 12, 2025

Southwinds Motel
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is P25,168 per night from 9 Mar to 10 Mar
P25,168
P29,305 total
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Southernmost Point and Duval Street are ...
9.4/10 Exceptional! (29 reviews)
"Beautiful property and friendly staff!"

Reviewed on Feb 15, 2025

Douglas House
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is P31,756 per night from 23 Feb to 24 Feb
P31,756
P37,506 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service, and parking (surcharge). Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,003 reviews)
"Perfect get away"

Reviewed on Feb 16, 2025

The Mansion on the Sea - Southernmost House in the USA
See all 2,955 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

If you're spending some time in Old Town Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Ernest Hemingway Home and Museum.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval