![](https://mediaim.expedia.com/destination/2/f1e37b506e93b4540247ee4d92162d8a.jpg?impolicy=fcrop&w=1200&h=300&q=medium)
Illinois Medical District Trips (flight + hotel)
- Plan, book, travel with confidence
Better together
Save up to P 3,118 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Illinois Medical District
Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Illinois Medical District
![Downtown Chicago showing a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/332000/332072-Downtown-Chicago.jpg?impolicy=fcrop&w=350&h=192&q=medium)
Downtown Chicago
5 out of top 10 points of interest in this area
Known for its fascinating museums, stunning river views, and gorgeous architecture, there's plenty to explore in Downtown Chicago. Top attractions like Michigan Avenue and Navy Pier are major draws. Catch the metro at State Station or Clark-Lake Station to see more of the city.
Top hotels in Illinois Medical District
![River Hotel](https://images.trvl-media.com/lodging/3000000/2680000/2675400/2675313/a97325e3_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
River Hotel
75 East Wacker Drive, Chicago, IL
Fully refundableReserve now, pay when you stay
The price is P4,720 per night from 5 Mar to 6 Mar
P4,720
P5,541 total
includes taxes & fees
Mar 5 - Mar 6
8.6/10 Excellent! (3,801 reviews)
"Biggest downsides to the property is that you are adjacent to Wacker and Michigan - both have high possibilities for noise (sirens, honking, etc) which I dealt with during my stay. Good dining options in the area, many within a 5 minute walk. Room size was fairly compact, but for a one night stay ..."
Reviewed on Feb 17, 2025
![Congress Plaza Hotel](https://images.trvl-media.com/lodging/1000000/10000/6500/6452/e43f096f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Congress Plaza Hotel
520 South Michigan Avenue, Chicago, IL
Fully refundableReserve now, pay when you stay
The price is P4,956 per night from 26 Feb to 27 Feb
P4,956
P5,818 total
includes taxes & fees
Feb 26 - Feb 27
7.8/10 Good! (8,481 reviews)
"Good spot to the lake shore, but it is very crowded in the elevator."
Reviewed on Feb 15, 2025
![L7 Chicago by LOTTE](https://images.trvl-media.com/lodging/1000000/10000/4200/4200/20c6522e_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
L7 Chicago by LOTTE
225 N Wabash Ave, Chicago, IL
Fully refundableReserve now, pay when you stay
The price is P7,462 per night from 23 Feb to 24 Feb
P7,462
P8,760 total
includes taxes & fees
Feb 23 - Feb 24
9.6/10 Exceptional! (1,634 reviews)
Fantastic hotel
"This might be the best hotel in the area."
Reviewed on Feb 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Things to do
![The Chicago Helicopter Tour 25 Miles](https://mediaim.expedia.com/localexpert/49372529/b4180bc6-eaea-4b45-9bcc-293144eaa526.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Chicago Helicopter 25-Mile Tour for up to Three Passengers
P37,920
per traveler
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.