Global Rent a Car Car Rental Deals in Santiago

Pick-up and drop-off

Same as pick-up

Pick-up time

Drop-off time

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Heading to Santiago? Explore Santiago with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more!

Members save 10% or more on over 100,000 hotels worldwide when you’re signed in