Taking into account the local weather in Esquipulas is an important factor for planning your visit, especially if you plan to spend your trip poolside. The hottest months are usually April and May with an average temp of 78°F, while the coldest months are January and December with an average of 72°F. The rainiest months in Esquipulas are June, September, July, and August, with each month seeing an average of 11 inches of rainfall.