Defiance Hotels

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Top 10 trending Defiance hotels

Country Inn & Suites by Radisson, St. Charles Historic District
Enjoy a delicious breakfast at our hotel's breakfast bar, featuring a variety of baked goods, bowls, and a coffee machine.

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Very Nice area with lots of shops and restaurants, clean comfortable rooms with very friendly staff, and good morning breakfast. "
The price is P6,434
P7,394 total
includes taxes & fees
Jul 20 - Jul 21
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis Chesterfield
Experience the contemporary look of The Drury Plaza Hotel, featuring a curved corner facade and bold, red signage.

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Great place!"
The price is P7,343
P8,516 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel St. Louis Chesterfield
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Enjoy a variety of food options at our self-service buffet with multiple stations.

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

2.5 star property
9.2 out of 10, Wonderful, (904)
"Great place to stay. Felt safe and secure there"
The price is P4,926
P5,731 total
includes taxes & fees
Aug 1 - Aug 2
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Wingate by Wyndham St. Louis/Fenton Route 66
Two single beds with white linens and a patterned bed runner, each with a bedside table and lamp.

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
8.4 out of 10, Very Good, (1028)
"Decent hotel for its price!"
The price is P5,041
P5,822 total
includes taxes & fees
Jul 20 - Jul 21
Wingate by Wyndham St. Louis/Fenton Route 66
MainStay Suites St Louis Airport
Guests can find a selection of beverages and snacks in this well-maintained corridor.

MainStay Suites St Louis Airport

3.0 star property
8.2 out of 10, Very Good, (288)
"Smooth stay with no issues."
The price is P5,541
P6,611 total
includes taxes & fees
Jul 27 - Jul 28
MainStay Suites St Louis Airport
Best Western Plus Washington Hotel
Relax in comfort with a large bed and desk area featuring a TV.

Best Western Plus Washington Hotel

2.5 star property
9.0 out of 10, Wonderful, (570)
"Great, clean property! Beds were comfortable, bathroom was clean! Nice outdoor area! Would stay again! "
The price is P7,287
P8,296 total
includes taxes & fees
Jul 20 - Jul 21
Best Western Plus Washington Hotel
Holiday Inn St. Louis - Creve Coeur by IHG
Experience a welcoming lobby with a reception area, comfortable seating, and a stylish rug.

Holiday Inn St. Louis - Creve Coeur by IHG

3.0 star property
8.8 out of 10, Excellent, (288)
"Nice place to stay."
The price is P5,603
P6,894 total
includes taxes & fees
Aug 3 - Aug 4
Holiday Inn St. Louis - Creve Coeur by IHG
Hampton Inn & Suites St. Charles Old Town Area
Relax in style with a spacious lobby featuring a central table, comfortable seating, and a large window.

Hampton Inn & Suites St. Charles Old Town Area

2.5 star property
9.0 out of 10, Wonderful, (535)
"The property was clean. Staff did a great job handling the crowd on the weekend for breakfast. It is in walking distance to the old town area and casino. "
The price is P5,425
P6,572 total
includes taxes & fees
Jul 27 - Jul 28
Hampton Inn & Suites St. Charles Old Town Area
Drury Inn & Suites Southwest St. Louis
Relax in the hotel lobby's central seating area, featuring a sofa and armchairs, a flat-screen TV, and a large window.

Drury Inn & Suites Southwest St. Louis

3.0 star property
9.4 out of 10, Exceptional, (1020)
"Great breakfasts; comfortable rooms"
The price is P6,495
P7,599 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Southwest St. Louis
Hyatt Place St. Louis/Chesterfield
Kitchen area with ample storage and a central island for food preparation.

Hyatt Place St. Louis/Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Excellent hotel "
The price is P7,575
P8,786 total
includes taxes & fees
Aug 3 - Aug 4
Hyatt Place St. Louis/Chesterfield
Cedar Creek
Stunning two-story building with a balcony and multiple windows, set amidst beautifully landscaped gardens.

Cedar Creek

3.0 star property
8.8 out of 10, Excellent, (235)
"was remote, close to tourist areas, clean. excellent breakfast provided with room. only problem was loud guests in hallways when we were trying to sleep."
Cedar Creek
Drury Plaza Hotel St. Louis Creve Coeur
Enjoy dining in our restaurant with comfortable seating and a variety of table options.

Drury Plaza Hotel St. Louis Creve Coeur

3.0 star property
9.2 out of 10, Wonderful, (1002)
"We really enjoyed our stay and will stay there again if needed. "
The price is P6,961
P8,092 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel St. Louis Creve Coeur
Hilton Garden Inn Chesterfield
Enjoy cooking in this well-equipped kitchen with a central island and stools, featuring a coffee machine, kettle, and utensils.

Hilton Garden Inn Chesterfield

3.0 star property
8.2 out of 10, Very Good, (756)
"Property was clean and the staff was friendly "
The price is P6,578
P7,654 total
includes taxes & fees
Jul 20 - Jul 21
Hilton Garden Inn Chesterfield
Sleep Inn & Suites O'Fallon MO - Technology Drive
Welcome to our hotel lobby, featuring a reception desk, comfortable seating area, and stylish rug.

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
8.8 out of 10, Excellent, (1007)
"Good place to stay"
The price is P4,830
P5,696 total
includes taxes & fees
Jul 20 - Jul 21
Sleep Inn & Suites O'Fallon MO - Technology Drive
The Wildwood Hotel
Enjoy a romantic dinner for two with fine china, linens, and elegant table settings.

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1543)
"Great location for our stay"
The Wildwood Hotel
Country Inn & Suites by Radisson, St. Peters, MO
Welcome to our reception area, where friendly staff are available to assist with your stay. Guests can check in and access amenities from the computer monitor and telephone.

Country Inn & Suites by Radisson, St. Peters, MO

2.5 star property
8.2 out of 10, Very Good, (1005)
"It was great stay"
The price is P5,562
P6,393 total
includes taxes & fees
Aug 3 - Aug 4
Country Inn & Suites by Radisson, St. Peters, MO
Drury Inn & Suites St. Louis St. Peters
Enjoy meals and drinks in this outdoor dining area with a view of the interior.

Drury Inn & Suites St. Louis St. Peters

3.0 star property
9.2 out of 10, Wonderful, (1011)
"Friendly staff, great breakfast, clean rooms!"
The price is P5,592
P6,428 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites St. Louis St. Peters
Hilton Garden Inn St. Louis/O'Fallon MO
Relax in our spacious lobby with comfortable seating and a warm atmosphere.

Hilton Garden Inn St. Louis/O'Fallon MO

3.0 star property
8.8 out of 10, Excellent, (688)
"Nice location, with a couple restaurants nearby. Quiet, clean, nice beds/pillows."
The price is P8,083
P9,585 total
includes taxes & fees
Aug 1 - Aug 2
Hilton Garden Inn St. Louis/O'Fallon MO
Marriott St. Louis West
Relax by the serene pool surrounded by lush greenery and mature trees.

Marriott St. Louis West

3.5 star property
8.6 out of 10, Excellent, (1002)
"Easily accessible on a beautiful property. Lots of shops and restaurants nearby"
The price is P8,801
P10,230 total
includes taxes & fees
Aug 1 - Aug 2
Marriott St. Louis West
Courtyard by Marriott St Louis Westport Plaza
Hotel complex with a large entrance and a covered Courtyard area.

Courtyard by Marriott St Louis Westport Plaza

3.0 star property
8.8 out of 10, Excellent, (1005)
"Very accommodating even gave us a late check out for a triathlon so we could shower afterwards"
The price is P6,044
P7,010 total
includes taxes & fees
Aug 1 - Aug 2
Courtyard by Marriott St Louis Westport Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Defiance

Trip time! Discover the wineries, parks, and history in Defiance.

See all hotels in Defiance

Frequently asked questions

What's the best place to stay in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Hollywood Casino & Hotel St. Louis and Wingate by Wyndham St. Louis/Fenton Route 66. See all available top hotels, or vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool, and buffet. Wingate by Wyndham St. Louis/Fenton Route 66 and Days Inn and Suites by Wyndham St. Louis/Westport Plaza are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium, and Gateway Arch. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.